Embolización percutánea del injerto renal afuncionante como alternativa terapéutica a la trasplantectomía quirúrgica

González-Satué, C.; Riera, Lluı́s; Franco, E; Castelao, Alberto Martínez; Sancho, C.; Ponce, A.; Serrallach, N

doi:10.1016/s0210-4806(00)72455-7

Cited by 4 publications

(12 citation statements)

References 12 publications

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“…The main cause of post-transplantation renal function loss, considering both groups, was chronic rejection with 43% of the cases according to 7 studies [ 18 , 29 , 31 , 35 , 38 , 39 , 42 ], followed by chronic graft nephropathy with 44.2%, as reported in 1 series [ 32 ], and acute rejections with 21.5% according to 6 studies [ 18 , 29 , 32 , 35 , 38 , 39 ]. In the transplantectomy group, the main cause was chronic graft nephropathy at 44.2% [ 32 ]; while in the embolization group, it was chronic rejection, at 77.5% [ 18 , 31 , 42 ] ( Table 1 ).…”

Section: Resultsmentioning

confidence: 98%

“…However, most of those studies were off-topic because they did not assess all-cause mortality or post-procedure complications. Finally, a total of 26 case series that satisfied all the methodological requisites ( Figure 1 ) were selected [ 7 , 8 , 12 , 13 , 16 – 18 , 24 – 42 ].…”

Section: Resultsmentioning

confidence: 99%

“…Twenty-six case series, with a total of 2421 patients, were included in this review. A total of 2232 patients (18 case series) [ 12 , 18 , 24 – 27 , 29 , 30 , 32 – 41 ] underwent transplantectomy, and the other 189 (9 case series) [ 7 , 8 , 13 , 16 – 18 , 28 , 31 , 42 ] underwent percutaneous embolization. Only 1 study reported on a pediatric patient [ 8 ] ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…Of the 26 studies, 2 were conducted in North America (Canada [ 33 ] and the United States [ 41 ]); 6 in Asia (China [ 28 , 29 ], India [ 35 , 39 ], Israel [ 8 ], and South Korea [ 36 ]); 16 in Europe (France [ 37 ], The Netherlands [ 12 , 27 ], Italy [ 16 , 31 ], Ireland [ 30 ], Portugal [ 26 ], Spain [ 7 , 13 , 17 , 18 , 24 , 38 , 42 ], and the United Kingdom [ 25 , 40 ]); 1 in Eurasia (Turkey [ 34 ]); and 1 in South America (Brazil [ 32 ]) ( Table 1 ).…”

Section: Resultsmentioning

confidence: 99%

“…The morbidities specific to embolization were post-embolization syndrome and need for transplantectomy after embolization. The post-embolization syndrome was defined as low fever after the embolization procedure (either associated or not associated with local pain), non-specific malaise, increase in graft size, and hematuria [ 13 , 16 – 18 ].…”

Section: Methodsmentioning

confidence: 99%

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Nephrectomy Versus Embolization of Non-Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis

et al. 2018

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There is no standardization on the timing of the best approach to treat a non-functioning renal graft.We reviewed the literature and performed a proportional meta-analysis of case series of transplantectomy and embolization for a non-functioning renal graft. The groups were compared for mortality and morbidity outcomes.A total of 2421 patients were included in this review. Of these, 2232 patients underwent transplantectomy and 189 underwent percutaneous embolization. The mortality rate in the nephrectomy group was 4% [95% confidence interval [CI], 2–7%; I2=87%] as compared with 0.1% [95% CI, 0.1–0.5%; I2=0%] in the embolization group. The rates of common morbidities were 18% [95% CI, 13–26%, I2=79.7%] for nephrectomy compared with 1.2% [95% CI, 0.7–2.1%, I2=26.4%] for embolization. The incidence of post-embolization syndrome was 68%, and 20% of patients needed post-embolization nephrectomy.Percutaneous embolization was associated with lower mortality and morbidity rates but also with a high rate of post-embolization syndrome. However, in most cases this complication had easily manageable symptoms. Embolization is a new and attractive technique that can be considered in treating non-functioning renal grafts.

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Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 3 more Smart Citations

Nephrectomy Versus Embolization of Non-Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis

et al. 2018

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Transplant nephrectomy after graft failure: is it so risky? Impact on morbidity, mortality and alloimmunization

et al. 2018

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Timing of Return to Dialysis in Patients with Failing Kidney Transplants

Molnar

Ichii

Lineen

et al. 2013

Seminars in Dialysis

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In the last decade, the number of patients starting dialysis after a failed kidney transplant has increased substantially. These patients appear to be different from their transplant‐naïve counterparts, and so may be the timing of dialysis therapy initiation. An increasing number of studies suggest that in transplant‐naïve patients, later dialysis initiation is associated with better outcomes. Very few data are available on timing of dialysis reinitiation in failed transplant recipients, and they suggest that an earlier return to dialysis therapy tended to be associated with worse survival, especially among healthier and younger patients and women. Failed transplant patients may also have unique issues such as continuation of immunosuppression versus withdrawal or the need for remnant allograft nephrectomy with regard to dialysis reinitiation. These patients may have a different predialysis preparation work‐up, worse blood pressure control, higher or lower serum phosphorus levels, lower serum bicarbonate concentration, and worse anemia management. The choice of dialysis modality may also represent an important question for these patients, even though there appears to be no difference in mortality between patients starting peritoneal versus hemodialysis. Finally, failed transplant patients returning to dialysis appear to have a higher mortality rate compared with transplant‐naïve incident dialysis patients, especially in the first several months of dialysis therapy. In this review, we will summarize the available data related to the timing of dialysis initiation and outcomes in failed kidney transplant patients after returning to dialysis.

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Embolización percutánea del injerto renal afuncionante como alternativa terapéutica a la trasplantectomía quirúrgica

Cited by 4 publications

References 12 publications

Nephrectomy Versus Embolization of Non-Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis

Nephrectomy Versus Embolization of Non-Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis

Transplant nephrectomy after graft failure: is it so risky? Impact on morbidity, mortality and alloimmunization

Timing of Return to Dialysis in Patients with Failing Kidney Transplants

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