Embryotoxicity assays for leached components from dental restorative materials

Libonati, A; Marzo, Giuseppe; Klinger, Francesca Gioia; Farini, Donatella; Gallusi, G; Tecco, Simona; Mummolo, Stefano; Felici, Massimo De; Campanella, Vincenzo

doi:10.1186/1477-7827-9-136

Cited by 25 publications

(18 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many patients go to the dentist to improve and correct their smile, in order to achieve a more pleasant and natural appearance. The dentist can meet and satisfy the patient's esthetic needs by modifying the morphological and chromatic characteristics (shape and color) of the teeth, adopting increasingly effective techniques of adhesive and restorative dentistry …”

Section: Introductionmentioning

confidence: 99%

The relationship of tooth shade and skin tone and its influence on the smile attractiveness

Murro

Gallusi

Nardi

et al. 2019

J Esthet Restor Dent

Self Cite

View full text Add to dashboard Cite

Objective: The purpose of this clinical study was to determine if skin tone and tooth color had the same influence on smile attractiveness. Materials and Methods:A woman's smile photograph was digitally manipulated to create a range of images with varying colors. The skin shade was modified to create four tones (p1: light, p2: light medium, p3: medium dark, p4: dark) using the L'Oreal True Illusion shade as a guide. The tooth shade was modified in four different tones: A1, A2, A3, A4 using the VITAPAN Classical shade guide to produce 16 images. A sample of 328 participants rated each image for attractiveness by means of a visual analog scale (VAS). Comparison among groups was performed with a 2-way ANOVA adjusted for multiple comparisons with the Bonferroni test (α = .05).Results: Image (p3-a1) showed the highest VAS values, while image (p1-a4) obtained the lowest, (Bonferroni Test: a1 vs a2, a3, a4 P < .001; p3 vs p1, p2, p4 P < .001).Analysis performed for age, sex, level of education, and laypeople/dentists were not statistically significant (P > .05). Conclusions:Variations in tooth and skin tone can significantly influence the perception of smile attractiveness. In the tested conditions, a brighter tooth shade significantly affected the attractiveness of the smile independently from skin tone.Clinical Significance: Understanding patient and dentist perception of the attractiveness of a smile with the important role-played by skin tone, may help clinicians to better identify teeth shade, helping delivery of tailored prostheses and esthetic restorations. K E Y W O R D S chroma, esthetics, skin tone, smile attractiveness, tooth color, value

show abstract

Section: Introductionmentioning

confidence: 99%

The relationship of tooth shade and skin tone and its influence on the smile attractiveness

Murro

Gallusi

Nardi

et al. 2019

J Esthet Restor Dent

Self Cite

View full text Add to dashboard Cite

show abstract

“…In relation to potential hazards, a study by Libonati et al. [ 95 ] demonstrated that leaked components from nanocomposite materials caused embryotoxicity in mouse blastocyst in vitro , but the reverse was the case with no toxicity when subcutaneously implanted in vivo . Similarly, a lower toxicity was recorded for orthodontic adhesive nanocomposite composed of titanium dioxide (TiO 2 ) NPs (at 1% by weight of TiO 2 NPs) compared to the NP free material [ 96 , 97 ].…”

Section: Nanodentistry and Maxillofacial Pathologymentioning

confidence: 99%

Prospects of nanodentistry for the diagnosis and treatment of maxillofacial pathologies and cancers

Adeola

Sabiu

Adekiya

et al. 2020

Heliyon

View full text Add to dashboard Cite

Despite the commendable milestones achieved in molecular maxillofacial pathology in the last decade, there remains a paucity of utilization of ancillary nanomolecular tools that complement the omics-based approaches. As the advent of omics science transforms our understanding of tumour biology from a phenomenological to a complex network (systems-oriented) paradigm, several ancillary tools have emerged to improve the scope of individualized medicine. Targeted nano drug delivery systems have significantly reduced toxicity of chemotherapeutic agents in a precise manner. Many conventional cancer therapies are limited in efficacy and this has led to the emergence of nanomedical innovations. Despite the success of nanomedicine, a major challenge that persists is tumour heterogeneity and biological complexity. A good understanding of the interaction between inorganic nanoparticles and the biological systems has led to the development of better tools for individualized medicine. Tools such as the composite organic-inorganic nanoparticles (COINs) and the quantum dots (QD) have significantly improved the identification and quantification of disease biomarkers, histopathological detection methods, as well as improving the clinical translation and utility of these nanomaterials. Nanomedicine has lent credence to several multipronged theranostic applications in medicine, and this has improved the medical practice tremendously. Despite the palpable influence of nanomedicine on the delivery of individualized medical therapies, the term “nanodentistry” remains in the background without much hype, albeit some progress has been made in this area. Hence, this review discusses the potential and challenges of nanodentistry in the diagnosis and treatment of maxillofacial pathologies, particularly cancer in resource-limited settings.

show abstract

“…It was concluded that incorporation of 1% by weight of Ti0 2 nanoparticles to the composite structure does not result in additional health hazards compared to that occurring with pure adhesive. [ 59 ] In another study,[ 60 ] it was reported that leached components from composite material induced embryotoxicity in mouse blastocyst in vitro , while no toxicity was observed when subcutaneously implanted in vivo .…”

Section: Hazards Of Nanoparticlesmentioning

confidence: 99%

Nanotechnology and its application in dentistry

Abiodun-Solanke

Ajayi

Arigbede

2014

Ann Med Health Sci Res

View full text Add to dashboard Cite

Nanotechnology influences almost every facet of everyday life from security to medicine. The concept of nanotechnology is that when one goes down to the bottom of things, one can discover unlimited possibilities and potential of the basic particle. In nanotechnology, analysis can be made to the level of manipulating atoms, molecules and chemical bonds between them. The growing interest in the dental applications of nanotechnology is leading to the emergence of a new field called nanodentistry. An electronic database search that included PubMed, MedLine, and Cochrane library was conducted. Key words used in the search are nanotechnology dentistry and applications. Language limitation was set as articles reviewed were only those written and published in English language. We did not search the gray literature. Initially, 52 articles were retrieved from the database, and articles considered were those published from 2008 to 2013. Eight articles that met the selection criteria were eventually selected and reviewed.

show abstract

Embryotoxicity assays for leached components from dental restorative materials

Cited by 25 publications

References 20 publications

The relationship of tooth shade and skin tone and its influence on the smile attractiveness

The relationship of tooth shade and skin tone and its influence on the smile attractiveness

Prospects of nanodentistry for the diagnosis and treatment of maxillofacial pathologies and cancers

Nanotechnology and its application in dentistry

Contact Info

Product

Resources

About