2008
DOI: 10.1086/525260
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Emergence of Endemic Serogroup W135 Meningococcal Disease Associated with a High Mortality Rate in South Africa

Abstract: Serogroup W135 has become endemic in Gauteng, South Africa, causing disease of greater severity than did the previous predominant serogroup A strain.

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Cited by 94 publications
(79 citation statements)
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“…26 MD is endemic, peaking between May and October. 27,28 The incidence rate was 0.44 per 100,000 in 2013 and 0.36 per 100,000 in 2014. The main capsular group-causing disease is MenW (67e77% of disease is MenACWY), followed by MenB.…”
Section: South Africamentioning
confidence: 98%
“…26 MD is endemic, peaking between May and October. 27,28 The incidence rate was 0.44 per 100,000 in 2013 and 0.36 per 100,000 in 2014. The main capsular group-causing disease is MenW (67e77% of disease is MenACWY), followed by MenB.…”
Section: South Africamentioning
confidence: 98%
“…Apontam também algumas diferenças no comportamento dos diferentes sorogrupos, por exemplo, ondas epidêmicas mais prolongadas quando associadas ao B 4 e graus distintos de gravidade, especialmente na doença meningocócica pelo sorogrupo W 19 .…”
Section: Discussionunclassified
“…A identificação do sorogrupo W como preditor do óbito por doença meningocócica é consistente com a literatura que sugere que a maior gravidade associada ao sorogrupo W esteja relacionada ao complexo clonal ST-11, que aceitase ser mais virulento 19,25 . Esse complexo clonal tem sido isolado no Brasil 26 .…”
Section: Indicadores Selecionados Do Município De Sãounclassified
“…In Saudi Arabia, serogroup W-135 gained dominance within only 2 years [6], followed by other countries, e.g. Turkey, South Africa, Nigeria, Argentina, also observing much higher proportions of W-135 [7].…”
Section: Introductionmentioning
confidence: 95%