Emergence of nutrigenomics and dietary components as a complementary therapy in cancer prevention

Abstract

Cancer is an illness characterized by abnormal cell development and the capability to in ltrate or spread to rest of the body. When this abnormal development progresses in solid tissues, such as an organ, muscle, or bone it is known as tumour, which can spread to other regions of the body via the blood and lymphatic systems. Nutrition is a critical and immortal environmental component in the development of all living organisms encoding the relationship between a person's nutrition and their genes. These interactions have a signi cant impact on the pharmacokinetic properties of bioactive dietary components, as well as their site of action/molecular targets. They have the ability to modify gene expression and persuade alterations in DNA and protein molecules, which is researched scienti cally in nutrigenomics. Nutrigenomics encompasses nutrigenetics, epigenetics, and transcriptomics, as well as other "omic" disciplines like proteomics and metabolomics, to explain the vast disparities in cancer risk among people with roughly similar life style. Clinical trials and researches have evidenced that alternation of dietary habits is potentially one of the key approaches for reducing cancer risk in an individual. In this article, we will target how nutrigenomics and functional food work as preventive therapy in reducing the risk of cancer.

Identification of Navicula Genus Isolated from Pari Island, Seribu Island Regency, Indonesia

“…Water microorganisms will form proteins when the nutrients in the cultivation medium are sufficient, and measurements are usually taken when entering the exponential phase. Srivastava et al (2022), if there is a lack of macronutrients, microalgae cells will experience a decrease in protein content followed by degradation of other cell components related to protein synthesis. Pinandoyo et al (2021) also stated that the nutritional content that can be utilized optimally would increase growth.…”

Wogonin, as a potent anticancer compound: From chemistry to cellular interactions

“…1,2 Investigations suggested that dietary phytochemicals can help to prevent cancer and even have been found to improve oncopatients' quality of life. [3][4][5] The molecular basis of these bioactive compounds' actions may provide new opportunities for the scientific community to create or enhance innovative treatment strategies to treat horrible illnesses, such as cancer, cardiovascular disease, and neurodegenerative disorders. A bioactive polyhydroxy flavone called wogonin (5,7-dihydroxy-8-methoxyflavone) was discovered in Scutellaria baicalensis Georgi.…”