Emerging Phytochemicals and Bioactive Compounds from a Desert Plant Prosopis cineraria (L.) Druce and Future Prospects

Islam, M. W.; Bloukh, Samir Haj; Edis, Zehra; Bhandare, Richie R.

doi:10.1007/978-3-030-20283-5_2

Cited by 4 publications

(7 citation statements)

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“…Polyphenols, flavonoids and further plant-based natural products have high inhibition potential against pathogens [ 39 , 40 , 41 , 42 , 43 , 44 ]. Plant-based antimicrobials depend on synergistic mechanisms among their multiple constituents [ 40 ].…”

Section: Introductionmentioning

confidence: 99%

“…The natural combination of all components is needed to ensure the same activity. Nevertheless, plants remain a rich source of promising biosynthesized antimicrobial agents for mankind and are used historically against ailments [ 39 , 40 , 41 , 42 , 43 , 44 , 45 ]. Aloe barbadensis Miller (AV) is a well-known, low-cost, easy-to-cultivate plant, which even grows in arid regions.…”

Section: Introductionmentioning

confidence: 99%

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Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials

2020

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Antibiotic resistance is an eminent threat for the survival of mankind. Nosocomial infections caused by multidrug resistant microorganisms are a reason for morbidity and mortality worldwide. Plant-based antimicrobial agents are based on synergistic mechanisms which prevent resistance and have been used for centuries against ailments. We suggest the use of cost-effective, eco-friendly Aloe Vera Barbadensis Miller (AV)-iodine biomaterials as a new generation of antimicrobial agents. In a facile, one-pot synthesis, we encapsulated fresh AV gel with polyvinylpyrrolidone (PVP) as a stabilizing agent and incorporated iodine moieties in the form of iodine (I2) and sodium iodide (NaI) into the polymer matrix. Ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FT-IR), x-ray diffraction (XRD), microstructural analysis by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) verified the composition of AV-PVP-I2, AV-PVP-I2-NaI. AV, AV-PVP, AV-PVP-I2, AV-PVP-I2-NaI, and AV-PVP-NaI were tested in-vitro by disc diffusion assay and dip-coated on polyglycolic acid (PGA) sutures against ten microbial reference strains. All the tested pathogens were more susceptible towards AV-PVP-I2 due to the inclusion of “smart” triiodides with halogen bonding in vitro and on dip-coated sutures. The biocomplexes AV-PVP-I2, AV-PVP-I2-NaI showed remarkable antimicrobial properties. “Smart” biohybrids with triiodide inclusions have excellent antifungal and promising antimicrobial activities, with potential use against surgical site infections (SSI) and as disinfecting agents.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials

2020

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“…A combination between biosynthesized nanocomposites with iodine content may have promising antimicrobial effects [69,85]. Essential oils of several plants like Prosopis cineraria (L.) Druce, allium sativum L. (garlic), zingiber officinale (ginger), curcuma longa (turmeric), cinnamomum zeylanicum (cinnamon) and rhus coriaria L. (sumac) have antimicrobial properties and support the immune system [69,[86][87][88][89][90][91][92]. In the Mediterranean, Middle-and Far-East many plants and essential oils are used due to their health benefits and antimicrobial activities [89].…”

Section: Plant Based Chemical Compoundsmentioning

confidence: 99%

Prevalence of COVID-19: A Look behind the Scenes from the UAE and India

Bloukh¹,

Shaikh²,

Pathan³

et al. 2020

Preprint

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Mankind faces a coronavirus pandemic originating from a seafood market in Wuhan, China since December 2019. The pathogen was named novel coronavirus (n-CoV) and bats are the identified key reservoir. The coronavirus disease 2019 (COVID-19) quickly spread over China across the globe, turned into a pandemic with exponentially increasing numbers of cases and significant mortality rate. China reacted with lockdowns and strict control measurements to prevent spreading the virus. The treatment of severe cases was hampered by lack of specific vaccines. Vaccine-development and production is a painstaking process and can only be enforced by international cooperation. Different supportive treatment options surfaced due to combinations of antiviral agents with antibiotic drugs. Elderly, male, immune-suppressed patients with co-morbidities showed a high mortality rate. Health literacy, strong immune system, adequate serum 25-hydroxyvitamin D (25(OH)D) concentrations and healthy life style choices can support fast recovery. Antibiotic resistance needs to be addressed by development of new generation antimicrobials against nosocomial infections in preparation for future outbreaks. Plant-biosynthesis of nanomaterials and antiseptics may help in prevention and recovery rate. Prevalence of COVID-19 maybe inversely related to BCG vaccination, endemicity of malaria, humidy and temperature but directly with latitude. Recommendations to prevent the spread of COVID-19 should be followed strictly.

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“…The qualitative chemical analysis of extracts of Prosopis pods was found positive for alkaloids, proteins, carbohydrates, flavonoids, glycosides, saponins, and tannins in alcohol and aqueous solvent extracts. Also, 11 amino acids have been isolated from leaves and pods viz; aspartic acid, glutamic acid, serine, glycine, histidine, threonine, arginine, alanine, proline, valine, tyrosine, methionine, cysteine, isoleucine, leucine, phenylalanine, and lysine 3 .…”

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confidence: 99%

“…Its bark is said to be a potent drug for several ailments such as leprosy, dysentery, bronchitis, asthma 6 , leucoderma, piles, muscular tremors, asthma, rheumatism and inflammations. Pharmacological activities like analgesic, antipyretic, antihyperglycemic, anti-oxidant, antihypercholesterolemic, anti-tumor, nootropic, anthelmintic, anti-bacterial, anti-fungal, anti-viral, and anticancer activities have also been reported from different plant extracts 3,[7][8][9][10][11][12][13][14] . The inhibitory activities of enzymes lipid peroxidase, cyclooxygenase -1 and-2 in sangri pods was also reported 15 .…”

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confidence: 99%

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2021

IJPSR

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This study was aimed to identify the possible bioactive chemical constituents of the state tree of Rajasthan, i.e., Prosopis cineraria L. (locally called Khejri) by GC-MS analysis using the GC-MS equipment (Shimadzu GCMSQP2010). For this purpose, the ethanolic extract of P. cineraria pods were used. Experimental conditions of the GC-MS system were as follows: Rtx-5MS capillary standard non-polar column, dimension: 30m, ID: 0.25 mm, Film: 0.25 µm was used, and flow rate of mobile phase (carrier gas: He) was set at 1.0 ml/min. Crude samples that were dissolved in methanol were run fully at a range of 40-550 m/z, and the results were compared by using NIST Library. GC-MS analysis of an ethanolic extract of pods led to the identification of 32 compounds viz. Bicyclo[3.1.1]hept-3-ene, 4, 6, 6-trimethyl-2-vi (30.47%), 5-Isopropyl-2methylbicyclo [3.1.0] hexan-2-ol(19.38%), (-)-.beta. -Bourbonene (10.62%), 3-O-Methyl-d-glucose (5.04%), Kessane (4.01%), Thunbergol (3.65%), alfa.-Copaene (2.23%). There is not much information available on the phytochemical constituents of P. cineraria pods. This is the first attempt to investigate the GC-MS analysis of the ethanolic extract of this plant. INTRODUCTION:The P. cineraria (L) Druce belonging to the family Leguminosae is an important tree (Khejri-a local name in Rajasthan) of the Thar Desert with hard climatic adaptation and is considered as one of the lifelines in desert habitat as mentioned in ancient literature. This is a species representing all five F viz., Forest, Fiber, Fuel, Fodder, and Food. Pods of Khejri are eaten by cattle, sheep, horses, mules, donkeys, goats, camels, and other wildlife in the desert, especially blackbuck and chinkara in the western Rajasthan have survived by eating pods and leaves of this tree. This tree is also of mythological importance in local communities.

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Emerging Phytochemicals and Bioactive Compounds from a Desert Plant Prosopis cineraria (L.) Druce and Future Prospects

Cited by 4 publications

References 40 publications

Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials

Facile Synthesis of Antimicrobial Aloe Vera-“Smart” Triiodide-PVP Biomaterials

Prevalence of COVID-19: A Look behind the Scenes from the UAE and India

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