Emphysematous cholecystitis

Yen, Wen-Lan; Hsu, Chi-Feng; Tsai, Ming-Jen

doi:10.1016/j.tcmj.2015.12.001

Cited by 2 publications

(9 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Emphysematous cholecystitis is a fulminant form of acute cholecystitis associated with an increased risk of gallbladder perforation and mortality due to differences in etiology and pathophysiology. While the clinical presentation of emphysematous cholecystitis is nearly indistinguishable from acute cholecystitis, the mortality rate of emphysematous cholecystitis is approximately 15% compared to that of uncomplicated acute cholecystitis at 1.4% [1][2][3], illuminating the importance of prompt diagnosis and intervention.…”

Section: Discussionmentioning

confidence: 99%

“…Emphysematous cholecystitis patients often have a history of vascular compromise, predisposing their gallbladder to ischemia, and diabetes mellitus, creating a microenvironment supporting anaerobic bacterial overgrowth [1][2][3][4][5]. Emphysematous cholecystitis is most commonly caused by anaerobic organisms, such as Clostridia spp., Klebsiella spp., Escherichia coli, Enterococci, and Anaerobic streptococci, infecting an ischemic gallbladder [1][2][3][4][5][6][7][8]. These bacteria are gas-producing and increase the chance of gallbladder rupture by stressing the already compromised organ structure [3][4].…”

Section: Discussionmentioning

confidence: 99%

“…Classic signs of acute cholecystitis can often lead to a more severe diagnosis upon radiologic indications such as a perforated emphysematous gallbladder. Also known as clostridial cholecystitis, this condition develops in 1% of the patients that are diagnosed with all cases of acute cholecystitis and is associated with high mortality (around 15%) due to perforation, which will be discussed in this patient's case [1][2][3]. Imaging studies are especially important in this case, as it identifies features of the gallbladder that classified this surgery as emergent.…”

Section: Introductionmentioning

confidence: 94%

“…The causes of an emphysematous gallbladder can range from diabetes, atherosclerotic disease, or infection from bacteria such as Clostridium perfringens, Escherichia coli, and Klebsiella spp. [1][2][3][4]. This case report will further examine the presenting signs and symptoms of a perforated emphysematous gallbladder to correlate future cases of a similar nature.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Perforated Emphysematous Cholecystitis: A Race Against Time

Misir¹,

Vahora²,

Unbehaun³

et al. 2023

Cureus

View full text Add to dashboard Cite

Emphysematous cholecystitis is a rare infection of the gallbladder that stems from acute cholecystitis. It can rapidly progress and perforate the gallbladder, which would require urgent surgical intervention. A perforated gallbladder can be diagnosed using an abdominal computed tomography by confirming the presence of air in the gallbladder lumen with adjacent extraluminal air. The causes of ruptured emphysematous cholecystitis include, but are not limited to, diabetes, atherosclerotic changes in blood vessels, and infection with Clostridium perfringens, Escherichia coli, and Klebsiella spp., and is usually present in diabetic men. We report on a 57-year-old female who developed gall bladder perforation with an overflow of gallstones into the peritoneum without a history of diabetes or atherosclerotic disease. Due to the vast availability of computerized tomography and early surgical intervention, the rate of mortality due to perforated emphysematous cholecystitis has decreased over the last few decades.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Perforated Emphysematous Cholecystitis: A Race Against Time

Misir¹,

Vahora²,

Unbehaun³

et al. 2023

Cureus

View full text Add to dashboard Cite

show abstract

“…Secondary bacterial infections in acute cholecystitis are commonly due to the enteric organisms Escherichia coli, Klebsiella, Streptococcus faecalis, and Enterococci [8,9]. Clostridium perfringens is uniquely seen in patients with EC [10].…”

Section: Introductionmentioning

confidence: 99%

Emphysematous Cholecystitis Secondary to Fusobacterium nucleatum

Kunadia¹,

Leong²,

Komanduri³

et al. 2021

Cureus

View full text Add to dashboard Cite

Fusobacterium nucleatum may be implicated in cases of emphysematous cholecystitis (EC) and carries a high mortality risk, especially in individuals with heart disease, renal insufficiency, and underlying malignancy. Fusobacterium infections are rarely detected in the setting of cholecystitis possibly due to the difficulty with properly culturing the bacteria. We describe a case of a patient with EC in whom blood cultures were positive for growth of F. nucleatum in one of two samples. The patient was treated with empiric antibiotic therapy consisting of metronidazole and cefepime. In patients with EC and negative cultures, it is possible that they may have an undetected infection with fusobacteria, which carries a high mortality risk. As such, clinicians should maintain a high degree of suspicion of obligate anaerobic infection in patients who have negative blood culture for growth in the setting of EC and consider continuation of adequate antimicrobial coverage.

show abstract

Emphysematous cholecystitis

Cited by 2 publications

References 4 publications

Perforated Emphysematous Cholecystitis: A Race Against Time

Perforated Emphysematous Cholecystitis: A Race Against Time

Emphysematous Cholecystitis Secondary to Fusobacterium nucleatum

Contact Info

Product

Resources

About