Emphysematous osteomyelitis caused by Salmonella typhi in beta thalassemia major

Doctor, PN; Verma, Mansi; Varaiya, A; R, Merchant

doi:10.4103/jpgm.jpgm_689_17

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…In one series of Salmonella osteomyelitis, 60 patients were noted to have hemoglobinopathies; 2 had sickle-thalassemia and 1 had sickle cell trait [5]. Additional case reports of patients with Salmonella osteomyelitis with thalassemia [6,7], thalassemia trait [8,9], sickle-thalassemia [[10], [11], [12], [13]], or sickle cell trait [14] have been reported.…”

Section: Discussionmentioning

confidence: 99%

Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association

Stephanie

Schmalzle

2019

IDCases

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Salmonella osteomyelitis is known to occur in immunocompromised and sickle cell disease patients. It rarely occurs in other hosts. We present a case of chronic femoral osteomyelitis due to S. enterica serovar Typhi seen in a Maryland resident. Potential risk factors included traveling to an endemic area as well as a newly diagnosed sickle cell trait and thalassemia trait. It is postulated that less severe hemoglobinopathies may also contribute to an elevated risk of Salmonella osteomyelitis.

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Section: Discussionmentioning

confidence: 99%

Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association

Stephanie

Schmalzle

2019

IDCases

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Emphysematous osteomyelitis of the clavicle: a pleural process?

et al. 2020

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Emphysematous osteomyelitis (EO) is a rare infection associated with intraosseous gas. EO is an often fatal disease with an estimated 34% mortality. We present a case of a 63-year-old man with sternoclavicular EO with pleural involvement and significant subcutaneous emphysema diagnosed by CT. Extension of intraosseous gas into the pleural cavity is an extremely interesting presentation that has not been previously reported. The patient underwent a multidisciplinary treatment approach with surgical debridement and an extended antibiotic course. Intraoperative cultures of the pectoralis muscle and bone biopsy grew pan-sensitive Escherichia coli. Prompt recognition and treatment are paramount to avoid a potentially fatal outcome. A review of the literature of the previous 46 cases of EO is presented for associated risk factors, the role of surgical management and antibiotic therapy.

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A case of emphysematous osteomyelitis in the pediatric practice

Okunev,

Okuneva,

Kalabkin

et al. 2023

Russian Journal of Pediatric Surgery

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Introduction. Emphysematous osteomyelitis is a life-threatening and rare disease in the clinical practice. A distinctive feature of the disease is gas in bones and in surrounding soft tissues on the background of predisposing factors which significantly worsen patient’s general condition (malignant neoplasms, diabetes mellitus, immunodeficiency, injuries and fractures). The authors present a clinical observation of diagnostics and management of emphysematous osteomyelitis in the right femur head in a 12-year-old child. The disease developed two months after a closed right-sided fracture of the femoral trochanter. In the literature, one can meet not more than 50 cases of emphysematous osteomyelitis. Relevance. In the available medical literature, we have not found any description of emphysematous osteomyelitis in children, so we considered it appropriate to publish a rare clinical case. Purpose. To analyze a rare case of emphysematous osteomyelitis in a child and to identify possible diagnostic and therapeutic errors occurred in the discussed case in Children’s Republic Clinical Hospital in Saransk. Conclusion. Currently, hematogenous osteomyelitis in children has become less common, and therefore there is no alertness for this pathology in physicians. We also have faced emphysematous osteomyelitis in our practice for the first time. Therefore, only when child’s condition worsened on day 4 after hospitalization, additional diagnostic tools were added, namely, X-ray of the knee and CT of the hip joint. Antibacterial therapy was started as well.

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Emphysematous osteomyelitis caused by Salmonella typhi in beta thalassemia major

Cited by 3 publications

References 10 publications

Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association

Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association

Emphysematous osteomyelitis of the clavicle: a pleural process?

A case of emphysematous osteomyelitis in the pediatric practice

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