In mobile networks, handover (HO) is one of the most important and complex KPIs (Key Performance Indicators), which directly affect to Quality of Service (QoS), Quality of Experience (QoE), and mobility performance. Moreover, its configuration parameters such as handover thresholds and handover neighbor lists are the key factors for implementing network optimization such as load balancing and energy saving. In a study before, the authors proposed clustering and forecasting models using ML algorithms and Time Series models to cluster, forecast, and manage the HO behavior of a huge number of cells. In this study, on the other hand, the authors firstly investigated more network KPIs to analyze their relationship with HO KPIs, and then, proposed new clustering, forecasting, and abnormal detection models that are expected to make them much more comprehensive. Finally, the performances of the proposed models were evaluated by applying them to a real dataset collected from the HO KPIs and other KPIs of more than 6000 cells of a real network during the years, 2016 and 2017. The results showed that the study was successful in identifying the relationship among network KPIs and significantly improving the performance of the HO clustering, forecasting, abnormal detection models. Moreover, the study also introduced the integration of emerging technologies such as machine learning (ML), big data, softwaredefined network (SDN), and network functions virtualization (NFV) to establish a practical and powerful computing platform for future self-organizing networks (SON).