Beam-target double spin asymmetries and target single-spin asymmetries in exclusive π + and quasi-exclusive π − electroproduction were obtained from scattering of 1.6 to 5.7 GeV longitudinally polarized electrons from longitudinally polarized protons (for π + ) and deuterons (for π − ) using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab. The kinematic range covered is 1.1 < W < 2.6 GeV and 0.05 < Q 2 < 5 GeV 2 , with good angular coverage in the forward hemisphere. The asymmetry results were divided into approximately 40,000 kinematic bins for π + from free protons and 15,000 bins for π − production from bound nucleons in the deuteron. The present results are found to be in reasonable agreement with fits to previous world data for W < 1.7 GeV and Q 2 < 0.5 GeV 2 , with discrepancies increasing at higher values of Q 2 , especially for W > 1.5 GeV. Very large target-spin asymmetries are observed for W > 1.6 GeV. When combined with cross section measurements, the present results can provide powerful constraints on nucleon resonance amplitudes at moderate and large values of Q 2 , for resonances with masses as high as 2.3 GeV.