Abstract. In order to design buildings that are resistant to earthquakes, first it is necessary to determine the parameters of ground motion. In this study, the earthquake seismic hazard analysis of the Old City Districts of Istanbul (Fatih and Eminonu) was probabilistically defined. For the analysis, the study zone was divided into 307 cells of 250 × 250 m using geographical information systems, and these cells were used in the mapping of all the data obtained. Then, for a building lifetime of 50 yr, the acceleration parameters of earthquake ground motions, peak ground acceleration, peak ground velocity, and spectral acceleration values of 0.2 s and 1 s were obtained at the bedrock level according to 10 % and 40 % exceedances. Additionally, in order to produce the artificial acceleration-time records of the ground movement in accordance with the NEHRP acceleration spectrum, the TARSCHTS computer simulation program was utilized. The results of the analysis showed that for the 10 % probability of exceedance, the peak bedrock acceleration values ranged from 0.30 g to 0.40 g, and for the 40 % exceedance probability the acceleration values ranged from 0.22 g to 0.17 g. The S s 10 % exceedance probability, calculated according to the spectral acceleration parameter, ranged from 0.67 g to 0.85 g and the spectral acceleration parameter S 1 varied between 0.22 g-0.28 g. The S s 40 % exceedance probability, calculated according to the spectral acceleration parameter, ranged from 0.46 g to 0.38 g and the spectral acceleration parameter S 1 varied from 0.12 g to 0.14 g.