Empty Nose Syndrome

Kuan, Edward C.; Suh, Jeffrey D.; Wang, Marilene B.

doi:10.1007/s11882-014-0493-x

Cited by 62 publications

(53 citation statements)

References 35 publications

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“…The correlation between changes in NOSE and PNIF values (r = −0.26, P = 0.02) was slightly lower than that reported by Lodder and Leong (r = −0.39) . This weak correlation may be related to differences in patient perception or experience of similar nasal function, differences in airflow turbulence, mucosal or neurosensory differences, the impact of nasal obstruction laterality, or other currently unknown factors …”

Section: Discussionmentioning

confidence: 56%

Peak nasal inspiratory flow is a useful measure of nasal airflow in functional septorhinoplasty

et al. 2018

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Objective To evaluate the utility of peak nasal inspiratory flow (PNIF) as a measure of nasal airflow and functional septorhinoplasty (FSRP) outcomes. Methods Patients with nasal obstruction were administered Nasal Obstruction Symptom Evaluation (NOSE) questionnaire and PNIF testing between January 2015 and 2018. Surgical patients repeated these tests at 2, 4, 6, 12, and 24 months postoperatively. Patient demographics and operative techniques were recorded. Results A total of 610 patients were evaluated for nasal obstruction with mean (standard deviation [SD]) NOSE score of 61.5 (23.2) and PNIF of 74.1 (35.4) liters per minute (L/min); correlation −0.16 (P < 0.001). Predictors of lower PNIF were female gender (β = −13.3, 95% confidence interval [CI] 7.7 to 18.2, P < .001) and higher NOSE scores (β = −0.43, 95% CI 0.19 to 0.68, P < 0.001). A total of 281 patients underwent FSRP with statistically and clinically significant improvements in both mean NOSE and PNIF scores that were stable out to 2 years. NOSE scores changed −41.0 (25.5) points, and PNIF improved 20.7 (35.5) L/min at last follow‐up. Grafting material did not affect outcomes, whereas spreader grafts improved PNIF values (β = 25.46, 95% CI 5.5 to 45.4, P = 0.013). Clinically significant changes between NOSE and PNIF were concordant, although the correlation was weak (r = −0.26, P = 0.02). Conclusion Peak nasal inspiratory flow is a rapid, cheap, and easily performed test that detects nasal obstruction and clinically significant improvements in airflow following FSRP. Although PNIF does not correlate well enough with the patient experience of nasal obstruction to be used as a diagnostic tool, it does provide unique and complementary information useful for evaluating, understanding, and improving the effects of surgical techniques. Level of Evidence 2C Laryngoscope, 129:594–601, 2019

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Section: Discussionmentioning

confidence: 56%

Peak nasal inspiratory flow is a useful measure of nasal airflow in functional septorhinoplasty

et al. 2018

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“…One of the strengths of our current study is the presentation of objective data on remnant inferior turbinate volume and its relationship with subjective symptoms in ENS patients. Previous studies have only focused on the subjective symptoms of these patients or were unable to clearly reveal the direct correlation between subjective symptoms and remnant turbinate tissue, which is strongly associated with aerodynamics, nasal humidification, temperature control, and mucociliary clearance of the nasal cavity . However, it was a single‐center study with a small number of subjects, and therefore the limited statistical power is main weakness of this study.…”

Section: Discussionmentioning

confidence: 94%

Correlation between remnant inferior turbinate volume and symptom severity of empty nose syndrome

Hong

Jang

2015

The Laryngoscope

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“…However, future studies could determine the prevalence of chronic rhinitis and osteomyelitis in a major population of dogs with nasal CTVT after chemotherapy. These findings represent common complications in dogs and humans after resection or destruction of turbinates. Previous studies have described CTVT in nasal cavities with a low metastatic rate .…”

Section: Discussionmentioning

confidence: 99%

Computer tomographic imaging in 4 dogs with primary nasal canine transmissible venereal tumor and differing cellular phenotype

Ojeda

Mieres

Soto

et al. 2018

Veterinary Internal Medicne

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Primary nasal canine transmissible venereal tumor (CTVT) without genital affection is uncommon. The aim of this report was to describe the primary nasal CTVT findings and CT staging in 4 dogs with different cytological phenotypes. Three male dogs and 1 bitch were evaluated for their chronic histories of sneezing, snoring, mucopurulent nasal discharge and nasal deformation. Cytological examination of nasal secretions suggested CTVT, confirmed by histopathological examination and LINE‐1/c‐myc. Males had the plasmacytoid phenotype of CTVT, and the bitch had the lymphocytoid phenotype. CTVT were staged based on the CT findings using modified Adams staging system. The bitch was classified as stage 1, 2 males were classified as stage 3 and 1 male as stage 4. All dogs had a complete tumoral remission after chemotherapy. Plasmacytoid phenotype was identified in cases with most important damage of the nasal cavity. However, the cytological type did not affect the response to chemotherapy.

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Empty Nose Syndrome

Cited by 62 publications

References 35 publications

Peak nasal inspiratory flow is a useful measure of nasal airflow in functional septorhinoplasty

Peak nasal inspiratory flow is a useful measure of nasal airflow in functional septorhinoplasty

Correlation between remnant inferior turbinate volume and symptom severity of empty nose syndrome

Computer tomographic imaging in 4 dogs with primary nasal canine transmissible venereal tumor and differing cellular phenotype

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