Emulsification Tendency of Silicone-Phenylsilicone Copolymer

Mechanical energy from intraocular instruments cause emulsification of silicone oil

“…11 12 Ikeda broadens the definition of emulsification to include large non-dispersed droplets, and suggests surface-active agent interactions are responsible for microscopic suspended oil, while mechanical energy results in large, non-dispersed emulsification. 15 However, we show that mechanical energy in vitro can give a microsuspension, which is comparable to the equivalent mechanical energy giving large non-dispersed droplets ex vivo. The architectural environment present intraocularly in vivo may permit large droplets to form, as we saw ex vivo, or the full-fill effect, 4 ex vivo may result in a lower level of emulsification in the form of larger bubbles.…”