Enamine Chemistry. V. Cycloaddition Reactions of Enamines Derived from Alicyclic Ketones

Synthesis and biological resolution of condensed bicyclic isoparaconic acid † derivatives

“…The reaction of 1-(morpholin-4-yl)cyclohexene 1 and diethyl maleate 2 (or fumarate), run at 25 ЊC in dry acetonitrile for 3 days, 7 afforded the bicyclo[4.2.0]octane derivative 3. X-Ray analysis 8 of the dimethyl analog of 3 revealed the cis fusion between the rings and the trans relationship between the two methoxycarbonyl groups.…”

Addition reactions of 1,1,1-trifluoro-4-trimethylstannylbut-3-yn-2-one and 1,1,1-trifluorobut-3-yn-2-one to some tetrahydropyridines. Synthesis of trifluoroacylated polysubstituted tetrahydroazocines

“…12, 16 Synthesis of azocines 3a-c was carried out under argon. 1 H and 13 C NMR spectra were recorded on a Bruker AMX 400 spec trometer (400 MHz ( 1 H) and 100 MHz ( 13 C)) in CDCl 3 . IR spectra were recorded on a Bruker IFS 25 spectrometer in Nujol.…”

Anionic polymerization of Lewis acid-activated methyl methacrylate by enamines

“…20,21 However, the reaction between 1b/1c and methyl acrylate requires more severe conditions (e.g., the reaction must be conducted in dioxane with refluxing for 66 h) than those in the present polymerization and, moreover, no reaction of 1 with MMA is known. 22 Obviously, complexation with 2 significantly enhances the electrophilic property of MMA.…”