Enantiomeric separation of β-blockers by HPLC using (R)-1-naphthylglycine and 3,5-dinitrobenzoic acid as chiral stationary phase

High‐Throughput Screening and Method Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE

“…These show enantiorecognition abilities toward a broad spectrum of chiral compounds, due to the higher-order structure of the chiral polysaccharide derivative polymers [32,33]. Many chemically different classes of chiral compounds can be resolved by these selectors [34][35][36][37][38][39][40][41].…”

Recent developments of enantioseparation techniques for adrenergic drugs using liquid chromatography and capillary electrophoresis: A review

“…The interactions of antagonists with the CSP are shown in Fig. 1; both enantiomers of the drugs produce different interactions with the CSP because of the different conformation [16,17].…”

Liquid chromatographic–electrospray tandem mass spectrometric determination of bisoprolol in human plasma

“…Prior to the prevalent use of LC-MS techniques, various analytical methods, such as capillary electrophoresis (Awadallah et al, 2003), gas chromatography (Kim et al, 2001) and HPLC with an ultraviolet (Zhang et al, 2003;Ruiz-Angel et al, 2002;Modamio et al, 1996), fluorescence (Buhring and Garbe, 1986;Eastwood et al, 1990;Suzuki et al, 1993) or diode array detector (Caudron et al, 2004), have been developed to determine bisoprolol in formulation and biological samples.…”