Enantioselective Hydrosilylation of Ketones with L*/[Rh(COD)Cl]2 and L*/[Ir(COD)Cl]2 Catalysts (L* = Ph2P(O)nCH2CH(NMe2)(CH2)mSMe (n = 0, 1; m = 1, 2))

Asymmetric hydrosilylation, transfer hydrogenation and hydrogenation of ketones catalyzed by iridium complexes

“…in the hydrosilylation of acetophenone by diphenylsilane (see Scheme 6) [16]. However, the reactions were slower, less enantioselective (e.e.…”

“…One interesting aspect is the reversal of enantioselectivity on going from Rh to Ir, observed experimentally in several cases [13][14][15][16]. Moberg has observed an increase of enantioselectivity, the extent of which depends on the nature of the anion, upon the addition of silver salts to the [MCl(COD)] 2 /L* precatalyst (M = Rh, Ir) (Scheme 7).…”

Application of palladacycle complexes in C-C, C-N and C-P bonds formation reactions

“…Hydrosilylation is often preferred because its reaction conditions are milder in which higher stereoselectivity of products was obtained comparison to the normal asymmetric hydrogenation (Scheme 1.37). [115]…”

“…[72] In the past decades, chiral heterobidentate P,N containing ligands, which are one of most important P,N containing ligands, are being intensively investigated because they have played extremely important roles in catalysis. They have been successfully applied in various asymmetric catalysis scenarios such as allylic alkylation, [73, 78, 108a, 119] hydrogenation, [74a, 83, 114, 120] hydrosilylation, [54,115,121] and hydroamination reactions [122] . In view of the above mentioned, developments in the preparation and application of a variety of P,N ligands has been rapid in recent years.…”

The Development of Bidentate P,N Ligands for Asymmetric Catalysis

“…[3] More recently, Anderson et al have applied Valphos (4) and the derivatives 12 ± 14 in the palladium-catalysed allylic alkylation of (E)-1,3-diphenylprop-2-enyl acetate (15), Scheme 2.…”