Enantioselective, potentiometric membrane electrodes based on cyclodextrins for the determination of l-histidine

Abstract

Four enantioselective, potentiometric membrane electrodes based on carbon paste impregnated with α-, β-, 2-hydroxyl-3-trimethylammoniopropyl-β-(as chloride salt) and γ-cyclodextrins (γ-CDs) are proposed for the assay of L-histidine (L-his). The proposed electrodes showed near-Nernstian response over L-his but not over D-histidine (D-his). The recovery of L-his in the presence of D-his was higher than 99.10% with R.S.D. lower than 0.1%. The surfaces of the electrodes are easily renewable by simply polishing on an alumina paper.

Efficient bienzyme nanocomposite film for chiral recognition of l-tryptophan, l-phenylalanine and l-tyrosine

“…Electrochemical sensors have attracted a lot of attention in the chiral discrimination of enantiomers due to their simplicity of operation and short response times. [26][27][28] Amperometric enzymebased biosensors in particular, have some distinct advantages in practical applications such as food control, considering that enzymes are highly selective and respond quickly to the specic substrate. 29,30 The essential factor in amperometric biosensor fabrication is the establishment of electrical communication between the redox centers of enzymes and common electrodes; electrode materials, electrolyte temperature and pH are also considered.…”

Electrochemical sensing of l-histidine based on structure-switching DNAzymes and gold nanoparticle–graphenenanosheet composites

“…Several sophisticated technologies including sensors/ biosensors, 9,10 potentiometry, 11 fluorescence with capillary electrophoresis, 12 voltammetry, 9 mass-spectrometry, 13 chromatography 14 and spectroscopy, 15 have been used for L-histidine detection. However, use of large sample volumes, expensive instrumentation, lack of reproducibility and selectivity, and eco-unfriendly solvents are serious concerns associated with these techniques.…”

Investigating the Prospect of Copper-Histidine Complex Modified Gold Electrode for Histidine and Human Serum Albumin Recognition

“…Histidine (His) is an essential amino acid for humans 1 and has a significant role in metabolism and wide range of physiological processes 2 , and measuring His concentration is of outmost importance. Analytical methods have been developed for the determination of histidine, such as chemiluminiscence 3 , high pressure liquid chromatography 4 , capillary electrophoresis 5 , potentiometric 6 , and recently, amperometric 7 method. However, expensive instrumentation, large sample volumes and use of eco-unfriendly solvents present disadvantages of these techniques.…”