Enantioselective Surface Plasmon Resonance Sensor Based on C₆₀ Fullerene‐Glutathione Self‐Assembled Monolayer (SAM)

Abstract

A novel enantioselective surface plasmon resonance (SPR) sensor based on a self-assembled monolayer of C60 fullerene as the chiral selector is proposed. A binding assay, apparent affinity constant, and apparent dissociation binding constant were used to analyze and study the enantioselectivity of C60 fullerene-glutathione film for L-histidine, which was chosen as the model analyte. The apparent affinity constant for the complex formed by L-histidine with C60 fullerene-glutathione film was 5.2 x 10(9) M(-1). The proposed SPR sensor can be used for the assay of L-histidine in the 10(-10)-10(-7) mol/L concentration range.

Plasmonic gas sensors based on nanomaterials: mechanisms and recent developments

“…Besides nanoparticles, several other nanomaterials have also been explored for their possible contributions in enhancing the performance of plasmonic sensors. Some of these include nanorods [92][93][94], nanowires [95][96][97][98][99], nanosheets [100][101][102], nanotubes [103,104], fullerenes [105,106], TM dichalcogenides, [107,108] hexagonal boron nitride [109,110], and core-shells [111][112][113]. Studies focussing on the integration of nanomaterials in plasmonics for sensing applications have led to breakthrough technologies such as wearable plasmonic sensors [114,115] and multi-parameter sensing [116][117][118].…”

Single-Molecule Fullerenes: Current Stage and Perspective

“…Fullerene materials have been widely used in semiconductor devices. Based on SAM devices, − many studies have also explored the properties and applications of fullerene materials at the molecular scale. ,− In contrast, the fabrication of single-molecule devices with a single fullerene molecule as the functional center is more challenging. Although there are many techniques for fabricating single-molecule devices, it is difficult for these devices to be stable, reliable, and reproducible.…”