Encapsulation of gold nanoparticles by simian virus 40 capsids

Wang, Tingjuan; Zhang, Zhiping; Gao, Dingshan; Li, Feng; Wei, Hongping; Liang, Xiaoyan; Cui, Zongqiang; Zhang, Xian-En

doi:10.1039/c1nr10568j

Cited by 39 publications

(31 citation statements)

References 33 publications

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“…SV40 VNPs have shown flexibility in packaging CdSe@ZnS QDs and AuNPs 29, 30. Moreover, SV40 VNPs can encapsulate CdSe@ZnS QDs regardless of their surface coating agents and surface charges since QDs coated with mercaptopropionic acid (MPA), DNA, neutrally charged polyethylene glycol (PEG) and positively charged PEG have been successfully encapsulated 31.…”

Section: Resultsmentioning

confidence: 99%

Three‐Dimensional Gold Nanoparticle Clusters with Tunable Cores Templated by a Viral Protein Scaffold

Chen

Zhang

et al. 2012

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Assembling nanoparticles (NPs) into ordered architectures remains a challenge in the field of nanotechnology. Templated strategies have been widely utilized for NP assembly. As typical biological nanostructures, virus-based NPs (VNPs) have shown great promise in templating NP assembly. Here it is illustrated that the VNP of simian virus 40 (SV40) is a powerful scaffold in directing the assembly of 3D hybrid nanoarchitectures with one NP encapsulated inside as a core and a cluster of gold NPs (AuNPs) on the outer surface of the SV40 VNP as a shell, in which the core NPs can be CdSe/ZnS quantum dots (QDs), Ag(2)S QDs, or AuNPs. The assembling of AuNPs onto the SV40 VNP surface is determined by the interactions between the AuNPs and the amine groups on the outer surface of SV40 VNPs. It is expected that the VNP guided 3D hybrid nanoarchitectures provide ideal models for NP interaction studies and open new opportunities for integrating various functionalities in NP assemblies.

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Section: Resultsmentioning

confidence: 99%

Three‐Dimensional Gold Nanoparticle Clusters with Tunable Cores Templated by a Viral Protein Scaffold

Chen

Zhang

et al. 2012

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“…The most widely used biological template for directed AuNP assemblies is DNA 21,22 , but also peptide fibrils 23 or protein fibres 2 were deployed as templates, for example, amyloid fibres for the construction of conducting nanowires 2 . Another prominent example for proteinaceous assemblies is the patterning or encapsulation of metal NPs by virus capsids [24][25][26] . The great advantage of protein-based assemblies is the ability to store and tune information about precise structure, composition and interaction potential on the genetic level.…”

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confidence: 99%

Molecular protein adaptor with genetically encoded interaction sites guiding the hierarchical assembly of plasmonically active nanoparticle architectures

et al. 2015

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The control over the defined assembly of nano-objects with nm-precision is important to create systems and materials with enhanced properties, for example, metamaterials. In nature, the precise assembly of inorganic nano-objects with unique features, for example, magnetosomes, is accomplished by efficient and reliable recognition schemes involving protein effectors. Here we present a molecular approach using protein-based 'adaptors/ connectors' with genetically encoded interaction sites to guide the assembly and functionality of different plasmonically active gold nanoparticle architectures (AuNP). The interaction of the defined geometricaly shaped protein adaptors with the AuNP induces the self-assembly of nanoarchitectures ranging from AuNP encapsulation to one-dimensional chain-like structures, complex networks and stars. Synthetic biology and bionanotechnology are applied to co-translationally encode unnatural amino acids as additional site-specific modification sites to generate functionalized biohybrid nanoarchitectures. This protein adaptor-based nanoobject assembly approach might be expanded to other inorganic nano-objects creating biohybrid materials with unique electronic, photonic, plasmonic and magnetic properties.

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“…AuNPs with diameters from 10 nm to 50 nm can also be encapsulated. The encapsulation efficiency increases as the AuNP size becomes larger . Recently, Ag 2 S QDs coated with dihydrolipoic acid (DHLA) have also been successfully encapsulated by SV40 VNPs .…”

Section: Strategies For Vnp‐templated Fabrication Of Nasmentioning

confidence: 99%

Fabrication of Nanoarchitectures Templated by Virus‐Based Nanoparticles: Strategies and Applications

Wang

2013

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Biomolecular nanostructures in nature are drawing increasing interests in the field of materials sciences. As a typical group of them, virus-based nanoparticles (VNPs), which are nanocages or nanorods assembled from capsid proteins of viruses, have been widely exploited as templates to guide the fabrication of complex nanoarchitectures (NAs), because of their appropriate sizes (ca. 20-200 nm), homogeneity, addressable functionalization, facile modification via chemical and genetic routes, and convenient preparation. Foreign materials can be positioned in the inner cavity or on the outer surface of VNPs, through either direct synthesis or assembling preformed nanomaterials. Simultaneous use of the inner and outer space of VNPs facilitates integration of multiple functionalities in a single NA. This review briefly summarizes the strategies for fabrication of NAs templated by VNPs and wide applications of these NAs in fields of catalysis, energy, biomedicine, and nanophotonics, etc.

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Encapsulation of gold nanoparticles by simian virus 40 capsids

Cited by 39 publications

References 33 publications

Three‐Dimensional Gold Nanoparticle Clusters with Tunable Cores Templated by a Viral Protein Scaffold

Three‐Dimensional Gold Nanoparticle Clusters with Tunable Cores Templated by a Viral Protein Scaffold

Molecular protein adaptor with genetically encoded interaction sites guiding the hierarchical assembly of plasmonically active nanoparticle architectures

Fabrication of Nanoarchitectures Templated by Virus‐Based Nanoparticles: Strategies and Applications

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