Endobronchial Management of Advanced Lung Cancer

Simoff, Michael

doi:10.1177/107327480100800405

Cited by 42 publications

(16 citation statements)

References 43 publications

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“…15 followed by chest pain (73.3%), breathlessness (46.6%), hemoptysis (12%), hoarseness of voice (11.6%) and fever in 13 (43.3%), anorexia in 11(36.6%), weight loss in 10 (33.3%), hoarseness of voice and hemoptysis in 5 (16.6%) and dysphagia in 1 (3.3%) comparable in frequency to other studies. 16,17 Adenocarcinoma (46.6%) was found to be the commonest subtype among male and females. other entities like non-small cell carcinoma, large cell carcinoma was exclusively found in males.…”

Section: Discussionmentioning

confidence: 99%

Clinicopathological profile and yield of fibreoptic bronchoscopy in 30 cases of lung carcinoma

2017

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Background: The study aims to identify the diagnostic yield of bronchoscopy along with clinico-pathological profile of 30 confirmed cases of lung cancer during a 6-months period.Methods: A retrospective analysis was conducted on the diagnostic yield bronchial brushing (BB), bronchoalveolar lavage (BAL) and brush biopsy specimens obtained at fibre-optic bronchoscopy for patients with lung cancer and their clinico-pathological characteristics studied.Results: Of 30 patients who underwent fibre-optic bronchoscopy examination brush cytology was diagnostic in 17 patients (68%) brush biopsy in 5 patients (20%) and BAL cytology in 4 patients (16%) with adenocarcinoma in 13 patients (43%), non-small cell carcinoma in 1 (3%), large cell carcinoma in 1 (3%), squamous cell carcinoma in 5 (16%), small cell carcinoma in 5 (16%). The most common Symptom was cough in 25 (83%) followed by chest pain in 22 (73.3%), breathlessness in 14 (46.6%), fever in 13 (43.3%), anorexia in 11 (36.6%), weight loss in 10 (33.3%), hoarseness of voice and haemoptysis in 5 (16.6%) and dysphagia in 1 (3.3%).Conclusions: In bronchoscopic procedure the highest yield is of brush cytology with adenocarcinoma being the most common type with presenting complaint of cough and chest pain. The prevalence of lung cancer is more common among males and commonly being located in right upper lobe.

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Section: Discussionmentioning

confidence: 99%

Clinicopathological profile and yield of fibreoptic bronchoscopy in 30 cases of lung carcinoma

2017

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“…It is a treatment option for patients with an airway obstruction, alternative to laser, diathermia, photodynamic therapy and stent applications [10][11][12][13][14][15][16]. Cryotherapy with minimal complication ratios were reported to be a good tolerated method by Maiwant et al [17][18].…”

Section: Discussionmentioning

confidence: 99%

Acute histopathological effects of cryotherapy on lung tissue

Yoldaş¹,

Çakan²,

Çağırıcı³

et al. 2016

Curr Thorac Surg

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“…In addition, up to 50% of patients receiving external radiation for local control will develop disease progression within the radiated field [43]. RT can also lead to endobronchial necrosis, inflammation, and swelling and convert a partial obstruction into a total one [44]. This can lead to worsening collapse and post-obstructive pneumonia.…”

Section: External Beam Radiation Therapy and Brachytherapymentioning

confidence: 98%

The role of interventional pulmonary procedures in the management of post-obstructive pneumonia

Mehta

Cutaia²

2006

Curr Infect Dis Rep

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Post-obstructive pneumonia is the result of airway obstruction, commonly due to lung cancer. The majority of patients with lung cancer are non-operable and incurable at initial presentation. The clinical course of these patients is steadily downhill with complicating events such as post-obstructive pneumonia, respiratory failure, pleural effusion, and severe debilitation. Non-invasive conventional options for post-obstructive pneumonia include broad-spectrum antibiotics, combined with attempts at relieving the obstruction using radiation therapy. There is scant literature on the natural course of post-obstructive pneumonia, disease resolution, and optimal treatment. With the recent surge in technologic advances in interventional pulmonology, multiple airway recanalizaton options are now available. In this paper, we describe the causes of post-obstructive pneumonia, and the role of interventional pulmonary procedures in -establishing an open airway.

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Endobronchial Management of Advanced Lung Cancer

Cited by 42 publications

References 43 publications

Clinicopathological profile and yield of fibreoptic bronchoscopy in 30 cases of lung carcinoma

Clinicopathological profile and yield of fibreoptic bronchoscopy in 30 cases of lung carcinoma

Acute histopathological effects of cryotherapy on lung tissue

The role of interventional pulmonary procedures in the management of post-obstructive pneumonia

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