Endocarditis and Pulmonary Aspergillosis in a Horse

Pace, Lanny W.; Wirth, Norman R.; Foss, R.; Fales, William H.

doi:10.1177/104063879400600423

Cited by 32 publications

(19 citation statements)

References 12 publications

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“…These clinical signs were the most frequently reported signs in the cases of endocarditis admitted to Lie`ge University and in cases of endocarditis in the scientific literature. 1,6,9,10,11,[16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33] …”

Section: Case Definitionmentioning

confidence: 99%

Vegetative Endocarditis in Equids (1994–2006)

Porter

Saegerman

Galen

et al. 2008

Veterinary Internal Medicne

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Background: Endocarditis is a rare heart condition with variable clinical expressions in equids. Risk factors for this disease are incompletely understood.Objective: Describe risk factors for endocarditis in equids. Animals: One hundred and fifty-three equids admitted to Lie`ge University, 9 diagnosed with endocarditis and 144 free from endocarditis but admitted to the hospital with a differential diagnosis including this disease.Methods: Retrospective case-control study.Results: Equids with endocarditis were significantly younger (mean age 5 4.84 AE 5.74 years) than control equids (mean age 5 10.8 AE 7.73 years) (P 5 .01). No sex or breed predisposition was observed. Animals with hyperthermia (odds ratio [OR] 5 24.4; confidence interval [CI] 5 1.40-428), synovial distension (OR 5 13.4; CI 5 3.00-59.8), lameness (OR 5 6.52; CI 5 1.63-26.1), hyperglobulinemia (OR 5 26.4; CI 5 3.03-229), hypoalbuminemia (OR 5 11.4; CI 5 1.34-96.8), hyperfibrinogenemia (OR 5 9.81; CI 5 1.16-82.7), or leukocytosis (OR 5 7.12; CI 5 1.40-36.4) presented a significantly higher risk of having endocarditis than control horses. The presence of two of the clinical signs mentioned above significantly increased the probability of a diagnosis of endocarditis (P .05).Conclusions and Clinical Importance: Age is associated with equine endocarditis. The diagnostic value of certain clinical signs and abnormalities in blood parameters in this disease are described.

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Section: Case Definitionmentioning

confidence: 99%

Vegetative Endocarditis in Equids (1994–2006)

Porter

Saegerman

Galen

et al. 2008

Veterinary Internal Medicne

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“…Mycotic pneumonia affects horses on glucocorticoid treatment and those with an overwhelming challenge by Aspergillus species (Ruoff, 1988). It is also seen in cases of hypercortisolemia associated with pituitary adenomas, ulcerative enterocolitis and myeloproliferative neoplasia (King, 1993;Pace et al, 1994;Buechner-Maxwell et al, 1994). The clinical signs of the disease include fever, lethargy, inappetence, slight tachypnea, increased respiratory rate, moderate increased bronchoalveolar sounds, recumbency and death.…”

Section: Mycotic Pneumonia (Pulmonary Aspergillosis)mentioning

confidence: 99%

Haematology and Clinical Biochemistry Findings Associated with Equine Diseases - a Review

Agina

2017

Not Sci Biol

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The course and outcome of a disease process is dependent upon factors such as the disease-causing agent and its cell tropism, defense mechanisms of the host, genetic resistance of the species or breed affected, as well as the age, nutritional status and hormonal levels of the affected animal. When haematology, clinical biochemistry and cytology test results are combined with other laboratory procedures, complete physical examination and also with the history of the patient, a veterinarian is well armed to arrive at a definitive diagnosis, make a certain prognosis (good, poor or guarded) and can also make a concluding statement on the efficacy of the instituted therapy. In clinical biochemistry, demonstration of specific enzyme activity and concentration of analytes in serum/plasma facilitates the disease diagnosis. Also, evaluation of haematology, clinical biochemistry and diagnostic cytology tests can help establish the presence or absence of diseases of internal organs, and by serial performance of these tests, may help to determine whether a disease process remains static, progressive or regressive. This review therefore provides the haematological, serum biochemical and cytological characteristics of diseases caused by the main bacteria, viruses, fungi, protozoa, helminths, arthropods, nutritional deficiencies, endocrine disturbances, neoplasm, allergy, toxins (phytoxins and zootoxins) and inorganic poisons in horses.

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“…Accordingly, disease usually occurs when host-debilitating conditions favor the penetration and the growth of these opportunistic fungi [6]. Pulmonary aspergillosis is clinically characterized by mild respiratory signs, tachypnea associated with adventitious lung or pleural sounds and fever [4,12,13]. Conversely, guttural pouch aspergillosis may cause epistaxis, dysphagia, soft palate paresis, pharyngeal paralysis, and laryngeal hemiplegia [7,9,[14][15][16].…”

Section: Introductionmentioning

confidence: 99%