2023
DOI: 10.3892/ijo.2023.5595
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Endocrine nuclear receptors and long non‑coding RNAs reciprocal regulation in cancer (Review)

Monica Cantile,
Margherita Cerrone,
Maurizio Di Bonito
et al.

Abstract: Nuclear receptors (NRs) are transcriptional regulators involved in different aspects of normal cell physiology. Their deregulation is associated with aberrant expression, gene mutations and/or epigenetic alterations that can be related to the pathogenesis of various human diseases, and especially in cancer. In particular, a complex genomic network involved in the development and progression of NR-mediated cancer has been highlighted. Advanced genomic technologies have made it possible to understand that the ex… Show more

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