Endocrinology of pregnancy loss

Luisi, Stefano; Lazzeri, Lucia; Genazzani, Andrea Riccardo

doi:10.3109/9780203931677.011

Cited by 2 publications

(2 citation statements)

References 64 publications

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“…6 Corpus luteum maintains its capacity to synthesise the progesterone throughout pregnancy but at approximately 7 th week of gestation its functional ability markedly decreases at the start of luteoplacental transition. 7 During the follicular phase of cycle serum progesterone remains low. Following Luteinizing hormone (LH) surge and ovulation, luteal cells in the ruptured follicle produces progesterone in response to LH.…”

Section: Steroidalmentioning

confidence: 99%

“…After that placenta becomes the main source of progesterone and level rises from 10-50 ng/ml in the first trimester to approximately 50-280 ng/ml in the third trimester. 6,7,9 If the amount or timing of progesterone release or the response of the endometrium to its stimulation is inadequate, the embryo fails in its attempt to achieve successful implantation resulting in infertility or spontaneous abortion. Serum progesterone is the reflection of the progesterone production by the corpus luteum which is stimulated by a viable pregnancy.…”

Section: Steroidalmentioning

confidence: 99%

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Evaluation of outcome of pregnancy in threatened abortion by serum progesterone levels

Kant

Ara

Lone

et al. 2015

Int J Reprod Contracept Obstet Gynecol

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Section: Steroidalmentioning

confidence: 99%

Section: Steroidalmentioning

confidence: 99%

Evaluation of outcome of pregnancy in threatened abortion by serum progesterone levels

Kant

Ara

Lone

et al. 2015

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

MMP-9 Level Comparation between Spontaneous Abortion and Normal Pregnancy

2012

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BACKGROUND: Abortion remains a problem in the obstetric care as it is one of the causes of maternal and fetal death. Bleeding or miscarriage threat in the first trimester comprises 20% to 25% of all pregnant women, and 50% of them will end as spontaneous abortion. The major cause of maternal death in abortion is hemorrhage. Some recent studies have indicated that MMP-9 is important in the process of embryo implantation into the endometrium and spontaneous abortion occurs when there is an overwhelming increase of MMP-9. This data indicate the importance of a further research to elucidate the role of MMP-9 in spontaneous abortion.METHODS: This was a cross sectional study, included 70 pregnant women with gestational age <20 weeks who came for examination and treatment at the Department of Obstetrics and Gynecology, Medical Faculty of Padjadjaran University/Hasan Sadikin Hospital, Bandung. RESULTS: There were differences in the MMP-9 levels in spontaneous abortion compared to normal pregnancy and MMP-9 had a cut-off point >1221.7 with the sensitivity of 48.6% specificity of 80%, and accuracy of 60.9%.SUMMARY: The MMP-9 level in spontaneous abortion was higher than in normal pregnancy.KEYWORDS: MMP-9, spontaneous abortion, normal pregnancy

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Endocrinology of pregnancy loss

Cited by 2 publications

References 64 publications

Evaluation of outcome of pregnancy in threatened abortion by serum progesterone levels

Evaluation of outcome of pregnancy in threatened abortion by serum progesterone levels

MMP-9 Level Comparation between Spontaneous Abortion and Normal Pregnancy

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