Endogenous benzoic acid interferes with the signatures of amino acids and thiol compounds through perturbing N-methyltransferase, glutamate-cysteine ligase, and glutathione S-transferase activity in dairy products

Jia, Wei; Wang, Xin; Shi, Lin

doi:10.1016/j.foodres.2022.111857

Cited by 8 publications

(2 citation statements)

References 25 publications

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“…This large abundance of benzoic acid in the produced vapor indicates that the PET fabric was converted into high-added value chemical products, which can be used in various applications such as the production of environmental radiocarbon monitoring, phenol, ointments, food, chemicals, pharmaceuticals, etc. [ 55 , 56 ]. Compared to the results of the catalytic pyrolysis of PET waste, which showed that 32 wt.% of the benzoic acid compound could be recovered at a temperature of 450–600 °C [ 57 ], the pyrolysis of PET fabric is very promising with a 134% increase in the benzoic acid abundance.…”

Section: Resultsmentioning

confidence: 99%

Pyrolysis Kinetic Behavior and Thermodynamic Analysis of PET Nonwoven Fabric

Yousef,

Eimontas,

Striūgas

et al. 2023

Materials

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This research aims to maximize polyethylene terephthalate (PET) nonwoven fabric waste and make it as a new source for benzoic acid extraction using a pyrolysis process. The treatment was performed using a thermogravimetric analyzer (TGA) and released products were characterized using FTIR spectroscopy and gas chromatography–mass spectrometry (GC–MS). The pyrolysis kinetic and thermodynamic behavior of PET fabric was also studied and simulated using different linear and nonlinear models. The results show that the PET fabric is very rich in volatile matter (80 wt.%) and can completely degrade under 490 °C with a weight loss of 84%. Meanwhile, the generated vapor was rich in the carbonylic C=O functional group (FTIR), and the GC–MS analysis concluded that benzoic acid was the major compound with an abundance of 75% that was achieved at the lowest heating rate (5 °C/min). The linear kinetic results showed that PET samples had an activation energy in the ranges of 193–256 kJ/mol (linear models) and ~161 kJ/mol (nonlinear models). The thermodynamic parameters, including enthalpy, Gibbs free energy, and entropy, were estimated in the ranges of 149–250 kJ/mol, 153–232 kJ/mol, and 256–356 J/mol K, respectively. Accordingly, pyrolysis treatment can be used to extract benzoic acid from PET fabric waste with a 134% increase in the benzoic acid abundance that can be recovered from PET bottle plastic waste.

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Section: Resultsmentioning

confidence: 99%

Pyrolysis Kinetic Behavior and Thermodynamic Analysis of PET Nonwoven Fabric

Yousef,

Eimontas,

Striūgas

et al. 2023

Materials

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“…Although the NCR pathway facilitates the adaptability of S. cerevisiae under various situations, it may additionally lead to the accumulation of certain non‐preferred nitrogen sources, like urea and arginine. This will not only lead to substrate waste but also cause the production of EC and food safety problems (Chen, Zeng, Yu, et al., 2022; Jia et al., 2022b; Zhang & Jia, 2024; Zhang, Du, et al., 2018). Consequently, the modification of NCR transcription factors, without the introduction of external genes, is considered to be a promising approach for reducing EC in fermented products.…”

Section: Construction Of Genetically Engineered Dominant Strains Redu...mentioning

confidence: 99%

Formation and hazard of ethyl carbamate and construction of genetically engineered Saccharomyces cerevisiae strains in Huangjiu (Chinese grain wine)

Li,

Jia

2024

Comp Rev Food Sci Food Safe

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Huangjiu, a well‐known conventional fermented Chinese grain wine, is widely consumed in Asia for its distinct flavor. Trace amounts of ethyl carbamate (EC) may be generated during the fermentation or storage process. The International Agency for Research on Cancer elevated EC to a Class 2A carcinogen, so it is necessary to regulate EC content in Huangjiu. The risk of intake of dietary EC is mainly assessed through the margin of exposure (MOE) recommended by the European Food Safety Authority, with a smaller MOE indicating a higher risk. Interventions are necessary to reduce EC formation. As urea, one of the main precursors of EC formation in Huangjiu, is primarily produced by Saccharomyces cerevisiae through the catabolism of arginine, the construction of dominant engineered fermentation strains is a favorable trend for the future production and application of Huangjiu. This review summarized the formation and carcinogenic mechanism of EC from the perspectives of precursor substances, metabolic pathways after ingestion, and risk assessment. The methods of constructing dominant S. cerevisiae strains in Huangjiu by genetic engineering technology were reviewed, which provided an important theoretical basis for reducing EC content and strengthening practical control of Huangjiu safety, and the future research direction was prospected.

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