Endokarditis: aktuelle Diagnostik und Therapie

Piper, Cornelia; Horstkotte, Dieter

doi:10.1007/s00063-008-1031-1

Cited by 2 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…drug abuse, or a previous history of IE. However, in 30 to 50%, no predisposing risk factors can be detected [ 2 , 3 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Dual-Pathogen Mitral Valve Endocarditis Caused by Coxiella burnetii and Streptococcus gordonii—Which Came First?

Kaemmerer,

Ciotola,

Geißdörfer

et al. 2023

Pathogens

View full text Add to dashboard Cite

Infective endocarditis (IE) is still a life-threatening disease with high morbidity and mortality. While usually caused by a single bacterium, poly-microbial infective endocarditis (IE) is rare. Here, we report a (blood-culture-negative) dual pathogen mitral valve IE caused by Coxiella burnetii and Streptococcus gordonii: A 53-year-old woman was presented to an internal medicine department with abdominal pain for further evaluation. Within the diagnostic work up, transthoracic echocardiography (TTE) revealed an irregularly shaped echogenic mass (5 × 13 mm) adherent to the edge of the posterior mitral valve leaflet and protruding into the left atrium. As infected endocarditis was suspected, blood cultures were initially obtained, but they remained negative. Chronic Q fever infection was diagnosed using serologic testing. After the occurrence of cerebral thromboembolic events, the patient was admitted for mitral valve surgery. Intraoperatively, a massively destructed mitral valve with adhering vegetations was noted. Examination of the mitral valve by broad-range bacterial polymerase chain reaction (PCR) and amplicon sequencing confirmed Coxiella burnetii infection and yielded Streptococcus gordonii as the second pathogen. Based on the detailed diagnosis, appropriate antibiotic therapy of both pathogens was initiated, and the patient could be discharged uneventfully on the 11th postoperative day after a successful minimal-invasive mitral valve replacement.

show abstract

“…drug abuse, or a previous history of IE. However, in 30 to 50%, no predisposing risk factors can be detected [ 2 , 3 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Dual-Pathogen Mitral Valve Endocarditis Caused by Coxiella burnetii and Streptococcus gordonii—Which Came First?

Kaemmerer,

Ciotola,

Geißdörfer

et al. 2023

Pathogens

View full text Add to dashboard Cite

show abstract

Role of Echocardiogram in Decision Making for Surgery in Endocarditis

Mestres

Fita

Azqueta

et al. 2010

Curr Infect Dis Rep

View full text Add to dashboard Cite

Infective endocarditis is a serious disease that carries significant morbidity and mortality. Adequate treatment is based on a high degree of clinical suspicion, accurate microbiologic diagnosis, and high-quality imaging. Echocardiography has been shown to be a fundamental tool for diagnosis and management. Currently accepted Duke criteria include blood cultures and echocardiography. Transthoracic and transesophageal echocardiography play a critical role in the decision-making process, especially when surgical treatment is contemplated. Because infective endocarditis is considered a medical and surgical disease, and considering that the current rate of surgery is about 50%, echocardiography has definite value in preoperative diagnosis and surgical planning, intraoperative confirmation of lesions and quality of repair or replacement before and after cardiopulmonary bypass, and postoperative assessment.

show abstract

Endokarditis: aktuelle Diagnostik und Therapie

Cited by 2 publications

References 15 publications

A Dual-Pathogen Mitral Valve Endocarditis Caused by Coxiella burnetii and Streptococcus gordonii—Which Came First?

A Dual-Pathogen Mitral Valve Endocarditis Caused by Coxiella burnetii and Streptococcus gordonii—Which Came First?

Role of Echocardiogram in Decision Making for Surgery in Endocarditis

Contact Info

Product

Resources

About