Endometrial cartilaginous metaplasia: A case report with literature review

Abstract

Endometrial metaplasias are of two types, epithelial metaplasia which is commonly encountered and stromal metaplasia, unusually seen. This includes formation within endometrial stroma, islands of smooth muscle, cartilage, and bone. Endometrial stromal (cartilaginous) metaplasias are conditions frequently overlooked and misdiagnosed. Hence, a careful clinical and histopathological examination is required to avoid the misinterpretation of non-tumor cartilaginous foci as a component of malignant neoplasm. Herein, we report a rare case of endometrial cartilaginous metaplasia which was an incidental finding in a 38-year-old female with third degree uterovaginal prolapse.

Osseocartilaginous metaplasia in the Endometrium: A Rare Reversible Cause of Secondary Infertility

“…[2] Because these cells are unusual at the site, this benign entity can be misinterpretated as malignancy. [1,3] There are several theories proposed for such metaplastic transformation. Most common factor being the chronic inflammation, especially genital tuberculosis in India.…”

“…Stromal metaplasia includes formation of islands of smooth muscle, cartilage, synovium, and bone. More than 100 cases have been reported in the world literature having either osseous or cartilaginous metaplasia in the endometrium but only one case report [1] documenting the combined osteo cartilaginous metaplasia has been identified till date. We put forward the second case having both the heterologous elements in the endometrium.…”

Midlife disorders

“…Unusual case reports as the ones in this edition[ 6 7 ] are important for all to read in order to diagnose such rarities if they confront us.…”