Endometrial patterns in abnormal uterine bleeding: a retrospective study

Kumari, Raj; Murugesan, Anuradha

doi:10.18203/2320-1770.ijrcog20175009

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Not Yet Classified: These consist of uterine isthmocele, arteriovenous abnormalities, and myometrial hyperplasia. PATTERNS OF AUB: (8,9,10) Menorrhagia: Heavy (> 80ml) or prolonged (> 7 days) menstrual flow. Hypomenorrhea (cryptomenorrhea): Menses which occur less than the average 28-day cycle (> 2 days).…”

Section: Figo Classification -Palm Coeinmentioning

confidence: 99%

Prevalence And Management Of Anaemia In Women With Abnormal Uterine Bleeding

et al. 2024

IJFMR

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Abnormal uterine bleeding is one of the common health concern affecting women of reproductive age, Abnormal uterine bleeding refers to the bleeding from the uterus that can be present in ways from infrequent episodes, to excessive flow or prolonged duration. The etiology varies with age, parity and may be attributed to both structural and non-structural causes(PALM COEIN)according to FIGO classification.It is a very frequent complaint that negatively affects the quality of life, hence, investigation for iron deficiency of anaemia is mandatory in these patients.The purpose of the recommendations, which include a list of side effects and indications for large blood loss, is to address the need to improve the lives of women. It was a Descriptive observational conducted to study the prevalence and management of Anaemia in women with abnormal uterine bleeding (AUB)in the department of Obstetrics and Gynecology, Malla Reddy Teaching Tertiary Care Hospital from August 2023 to January 2024. Details of 153 patients were recorded and analyzed with respect to age, parity, patterns, AUB according to PALM-COEIN, symptoms, treatment options were evaluated with menstrual history, physical examination, laboratory tests, pre and post iron supplementation for 4 weeks and were followed up from 1 to 2 months. The study shows that The age range of 41-45 years old has the highest prevalence of AUB (44%), AUB and anaemia are significantly correlated (by 60%) moderate anaemia patients are more, 25% of patients had mild anaemia. Iron Supplementation Efficacy is beneficial in controlling hematologic issues caused by AUB, as evidenced by the 80% of cases in which anaemia was successfully corrected. Adenomyosis (AUB-A) is the most common group (67%), according to the PALM-COEIN classification system, which improves our understanding of various aetiologies. Analysis of menstrual patterns. Parity study shows a possible connection-most notably, among women in their 31–35 years of age range-between birthing experiences and AUB. The requirement for blood transfusions highlights the severity range within the AUB patients and is most common in cases of severe blood loss (21.56%).AUB is a widespread problem that impacts millions of women globally.

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Section: Figo Classification -Palm Coeinmentioning

confidence: 99%

Prevalence And Management Of Anaemia In Women With Abnormal Uterine Bleeding

et al. 2024

IJFMR

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Histopathological Study of Endometrium in Women With Abnormal Uterine Bleeding

Deshmukh

Malpani

Gosavi

et al. 2021

ijsr

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BACKGROUND –Abnormal uterine bleeding (AUB) is dened as a bleeding pattern that differs in frequency, duration and amount from a pattern observed during a normal menstrual cycle. The term dysfunctional uterine bleeding (DUB) is used to describe abnormal uterine bleeding for which no specic cause has been found. AUB is one of the most common gynaecological problems. This study was done to evaluate histological patterns of endometrium in women with abnormal uterine bleeding. AIMS AND OBJECTIVE – To study various histological patterns of endometrium in abnormal uterine bleeding and correlate it with age, parity and symptoms. MATERIAL AND METHODS –This is a retrospective study, conducted in the Department of Pathology, in a tertiary care hospital from 1st July 2016 to 30th June 2019. Total 718 specimens with AUB were included in the study from the age group of 21 to 95 years. The specimens received were hysterectomy (74.65 %), endometrial biopsies (21.45%), dilatation and curettage (2.79 %) and transcervical resection of endometrium (1.11 %). RESULTS –The patients with AUB were mainly from the age group 41-50 years with menorrhagia as the chief complaint. Most of the women with AUB were multiparous (84.54%). The most common pattern observed on histopathological examination was proliferative endometrium (49.86%) followed by atrophic endometrium (10.31%). Malignancy was found in 2.23% (Endometrioid carcinoma – 1.81%, serous carcinoma - 0.14% and mucinous carcinoma – 0.28%). Endometrial hyperplasia without atypia (23 cases, 3.20%) was more common than endometrial atypical hyperplasia (EAH) / endometrioid intraepithelial neoplasia {EIN} (4 cases, 0.56 %). Various other patterns of endometrium on histopathology were endometritis (6.82 %) followed by endometrial polyp (4.46 %). CONCLUSION – Histopathological examination of endometrium should be done generously in women presenting with abnormal uterine bleeding especially after the age of 40 years to rule out malignant pathology.

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Endometrial blood vessel morphometry in patients presenting with abnormal uterine bleeding

Bhosale¹,

Arakeri²,

Reddy³

et al. 2022

Indian Journal of Pathology and Microbiology

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Background: Abnormal uterine bleeding (AUB) is one of the most common problems encountered in gynecological practice. Various benign and malignant disorders of the endometrial tissue show vascular changes such as congestion, dilatation, and vessel wall irregularities. Aim: To evaluate the vascular morphometry of the endometrial tissue in AUB. Materials and Methods: A descriptive cross-sectional study of the endometrial tissue in patients presented with AUB was undertaken for vascular morphometric analysis. Histopathological processing of the endometrial tissue samples was done as per the standard format, and the slides were evaluated for vascular morphometry. Results: Out of 150 cases of endometrial tissue in patients presented with AUB, 80 cases were reported as proliferative phase, 41 as secretory phase, 15 as disordered proliferative endometrium, 6 as atrophic phase endometrium, and 4 each of endometrial hyperplasia without atypia and endometrial carcinoma. An average number of endometrial blood vessels and large-sized blood vessels were more in endometrial carcinoma and endometrial hyperplasia without atypia as compared to proliferative phase, secretory phase, atrophic endometrium, and disordered proliferative endometrium. Vessel shape irregularities and vascular congestion were observed in all the cases of atrophic endometrium, endometrial carcinoma, and endometrial hyperplasia without atypia. Endometrial carcinoma showed severe dilatation of the endometrial blood vessels. Conclusion: Vascular morphometry changes were noted in endometrial hyperplasia, endometrial carcinoma, disordered proliferative endometrium, and atrophic phase endometrium. These findings suggest that studies or trials related to anti-angiogenic therapy may help to plan anti-angiogenic therapy in patients with AUB.

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Endometrial patterns in abnormal uterine bleeding: a retrospective study

Cited by 3 publications

References 5 publications

Prevalence And Management Of Anaemia In Women With Abnormal Uterine Bleeding

Prevalence And Management Of Anaemia In Women With Abnormal Uterine Bleeding

Histopathological Study of Endometrium in Women With Abnormal Uterine Bleeding

Endometrial blood vessel morphometry in patients presenting with abnormal uterine bleeding

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