Endoscopic evaluation of the therapeutic effect of sclerotherapy for esophageal varices

Miyoshi, Hirofumi; Matsumoto, Akio; Umegaki, Eiji; Oka, Masaki; Hirata, Ichirou; Ohshiba, Saburo

doi:10.1016/s0016-5107(93)70008-5

Cited by 14 publications

(9 citation statements)

References 16 publications

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“…Miyoshi et al . reported that prophylactic EIS improved survival in HCC patients with cirrhosis in comparison with those who did not receive EIS 8 . Moreover, Ogusu et al .…”

Section: Discussionmentioning

confidence: 98%

“…Miyoshi et al reported that prophylactic EIS improved survival in HCC patients with cirrhosis in comparison with those who did not receive EIS. 8 Moreover, Ogusu et al showed that prophylactic EIS might be more effective in prolonging long-term survival of patients with liver cirrhosis in the absence of HCC than emergency EIS. 9 EIS is an effective therapy for esophageal varices and is less invasive than surgery.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Gastric Ulcer After Endoscopic Injection Sclerotherapy for Esophageal Varices

Sato

Yamazaki

Toyota

et al. 2006

Digestive Endoscopy

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Background: Endoscopic injection sclerotherapy (EIS) is an effective procedure for the treatment of esophageal varices. In the present study, the pathogenesis of gastric ulcer after EIS for esophageal varices was investigated. Methods: EIS for esophageal varices was performed for 610 patients in our department, and the frequency and clinical course of gastric ulcer after EIS were investigated retrospectively. EIS was performed using 5% ethanolamine oleate with iopamidol, which was injected intermittently under fluoroscopy. Results: Gastric ulcer after EIS for esophageal varices was observed in 14 of the 610 (2.3%) patients. These were located around the cardia of the stomach from the fornix to the gastric body. Gastric ulcer extended from the stomach lining into the esophagus in 11 of the 14 cases. Severe chest pain was observed, and dark purple mucosal changes of the esophagus and stomach were detected endoscopically at the time of injection in all 14 cases. All cases received dripping therapy, and prescription of a proton pump inhibitor. Gastric ulcer after EIS was refractory, and almost 2 months was required until the healing stage was reached. Conclusion: Gastric ulcer after EIS for esophageal varices is a rare but important complication of EIS.

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“…Miyoshi et al . reported that prophylactic EIS improved survival in HCC patients with cirrhosis in comparison with those who did not receive EIS 8 . Moreover, Ogusu et al .…”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Evaluation of Gastric Ulcer After Endoscopic Injection Sclerotherapy for Esophageal Varices

Sato

Yamazaki

Toyota

et al. 2006

Digestive Endoscopy

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show abstract

“…[4][5][6][7][8][9][10][11][12][13][14][15][16][17]20 We previously showed that EIS prolonged survival in patients with esophageal varices complicated by liver cirrhosis with HCC, and that emergency and/or prophylactic EIS was effective in prolonging the survival period of HCC patients. 9,21,22 Miyoshi et al 23 showed that prophylactic EIS improved survival in HCC patients with liver cirrhosis compared with survival in those without EIS. In regard to liver cirrhosis patients without HCC, we demonstrated that EIS was more effective for prophylactic treatment of esophageal varices than EVL.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic injection sclerotherapy for esophageal varices in cirrhotic patients without hepatocellular carcinoma: a comparison of longterm survival between prophylactic therapy and emergency therapy

Ogusu

Iwakiri

Sakata

et al. 2003

Journal of Gastroenterology

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“…Of 133 cases with red color (RC) sign‐positive F 1 or more severe esophageal varices 9 treated by 1% AS in our hospital between June 1996 and December 2001, the subjects in this study comprised 44 cases with esophageal varices diagnosed as RC sign‐negative endoscopically and examined by EUS about 2 months after EIS (62.7 ± 26.5 days on average). Red color signs, as identified by endoscopy, indicate a high risk for bleeding from the esophageal varices 1,10 . The patients were examined by endoscopy every 3–6 months for 1 year or longer and the appearance of the RC signs was observed sooner or later.…”

Section: Methodsmentioning

confidence: 99%

“…Endoscopic injection sclerotherapy (EIS) has prevailed as a method to prevent and treat bleeding from esophageal varices with excellent efficacy 1–4 . However, early recurrence of esophageal varices after EIS occurs occasionally.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic Ultrasonography Findings and Clinical Backgrounds in Cases With Early Recurrence of Esophageal Varices After Endoscopic Injection Sclerotherapy

Ishii

Kakemura

Fujinuma

et al. 2005

Digestive Endoscopy

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Aims:To investigate the factors affecting early recurrence of esophageal varices after endoscopic injection sclerotherapy (EIS). Subjects and Methods: Forty-four cases with esophageal varices were examined by esophagogastroscopy and endoscopic ultrasonography (EUS) 2 months after EIS. Cases with and without red color (RC) signs evaluated within 1 year after EIS were classified as Early Recurrent Group (ERG) and Non-Early Recurrent Group (N-ERG), respectively, and compared with EUS images and clinical backgrounds. Results: Compared with ERG (17 cases), N-ERG (27 cases) had significantly higher detection rates of cardiac intramural veins (CV) and esophageal intramural veins (EV), larger maximum diameters of CV and EV, and higher numbers of CV (P < 0.05). The detection rates of gastric perforating veins (GPV)-but not esophageal perforating veins (EPV), paragastric veins (PGV), or paraesophageal veins (PEV)-correlated with recurrence of varices (P < 0.05). ERG differed in age, gender, g-glutamyltranspeptidase (GTP), and detection rates of portosystemic (PS) shunts from N-ERG (P < 0.05). Age, serum alanine aminotransferase (ALT) and g-GTP level, detection rates of PS shunt, maximum diameters of CV and EV, numbers of CV, and GPV-positive case differed (P < 0.10) by univariate analysis, and maximum diameters (hazard ratio (HR)), 7.16: 95% CI [1.45-35.33]; P = 0.016) and numbers (HR, 1.96: 95% CI, [1.02-3.75]; P = 0.043) of CV differed significantly between the two groups by multivariate analysis. Conclusions: EUS is useful in predicting recurrence of esophageal varices after EIS, and the degree of the development of CV is the most important critical factor for early recurrences.Key words: clinical backgrounds, diameter of cardiac intramural veins, endoscopic injection sclerotherapy, endoscopic ultrasonography, number of cardiac intramural veins.

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Endoscopic evaluation of the therapeutic effect of sclerotherapy for esophageal varices

Cited by 14 publications

References 16 publications

Evaluation of Gastric Ulcer After Endoscopic Injection Sclerotherapy for Esophageal Varices

Evaluation of Gastric Ulcer After Endoscopic Injection Sclerotherapy for Esophageal Varices

Endoscopic injection sclerotherapy for esophageal varices in cirrhotic patients without hepatocellular carcinoma: a comparison of longterm survival between prophylactic therapy and emergency therapy

Endoscopic Ultrasonography Findings and Clinical Backgrounds in Cases With Early Recurrence of Esophageal Varices After Endoscopic Injection Sclerotherapy

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