Endoscopic findings of <i>Helicobacter pylori</i> gastritis in children and young adults based on the Kyoto classification of gastritis and age‐associated changes

Hojo, Mariko; Nagahara, Akihito; Kudo, Toshifumi; Takeda, Tsutomu; Ikuse, Tamaki; Matsumoto, Keīichi; Ueyama, Hiroya; Matsumoto, Kenshi; Asaoka, Daisuke; Shimizu, Toshiaki

doi:10.1002/jgh3.12652

Cited by 15 publications

(14 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, other endoscopy findings related to H. pylori such as mucosal edema, diffuse rash, and antral hyperemia were also observed in these patients. It is acknowledged that H. pylori positive children may present various endoscopy findings besides antral nodularity (17). In our study, the most common endoscopic finding was antral hyperemia, followed by antral nodularity.…”

Section: Resultsmentioning

confidence: 52%

Can Saccharomyces boulardii treat and eradicate Helicobacter pylori among children instead of bismuth?

Başaran

ZENGİN

2022

Journal of Health Sciences and Medicine

View full text Add to dashboard Cite

Aim: The objective of this study is to compare the use of Saccharomyces boulardii (S. boulardii) in eradicating Helicobacter pylori (H. pylori) in children as an alternative to bismuth, which has a limited scope of application due to its side effects. Material and Method: Included in the study were 220 pediatric patients with symptomatic H. pylori gastritis. The patients were randomized into three treatment groups. Patients who received bismuth or S. boulardii in addition to the standard triple therapy for 14 days were compared with the control group who received only triple therapy. Results: Analysis of the bismuth, S. boulardii, and control groups’ treatment success showed that the H. pylori eradication rate was highest among study participants who received bismuth (95.2%), followed by patients who received S. boulardii (92.4%). The most frequent side effects were observed in the patient group that received bismuth (17.5%). Conclusion: Although bismuth continues to be successful in eradicating H. pylori, alternative treatment protocols are necessary because of its side effects and limited use in pediatric patients. S. boulardii can be administered instead when bismuth can not serve as alternative due to its side effects.

show abstract

Section: Resultsmentioning

confidence: 52%

Can Saccharomyces boulardii treat and eradicate Helicobacter pylori among children instead of bismuth?

Başaran

ZENGİN

2022

Journal of Health Sciences and Medicine

View full text Add to dashboard Cite

show abstract

“…Table 1 shows the endoscopic features of the stomach that are characteristic of patients with current H. pylori infection according to the Kyoto classification of gastritis [ 15 ]. They include atrophy, diffuse redness, foveolar-hyperplastic polyps, xanthomas, intestinal metaplasia, mucosal swelling, patchy redness, depressive erosions, enlarged and tortuous folds, sticky mucus, spotty redness, and nodularity.…”

Section: Discussionmentioning

confidence: 99%

“…Both patients had a white marble appearance in the lesser curvature of the gastric angle and antrum, and the authors speculated that the white marble appearance is a potential characteristic finding of non-Helicobacter pylori Helicobacter infection gastritis. Table 1 shows the endoscopic features of the stomach that are characteristic of patients with current H. pylori infection according to the Kyoto classification of gastritis [15]. ey include atrophy, diffuse redness, foveolar-hyperplastic polyps, xanthomas, intestinal mucosal swelling, patchy redness, depressive erosions, enlarged and tortuous folds, sticky mucus, spotty redness, and nodularity.…”

Section: Discussionmentioning

confidence: 99%

Helicobacter suis-Associated Gastritis Mimicking Conventional H. pylori-Associated Atrophic Gastritis

Iwamuro

Murayama

Nakamura

et al. 2022

Case Reports in Gastrointestinal Medicine

View full text Add to dashboard Cite

A 45-year-old Japanese man underwent esophagogastroduodenoscopy, which revealed spotty redness at the gastric fornix, mucosal swelling, diffuse redness in the corpus, and mucosal atrophy in the gastric angle and antrum. Histological examination showed rod-shaped bacteria that appeared larger than Helicobacter pylori. The patient tested positive for rapid urease test, and serum anti-H. pylori IgG antibody test results were negative. Further examination of the bacteria revealed that H. suis antibody test was positive, and the presence of H. suis was confirmed using H. suis-specific real-time PCR. H. suis was successfully eradicated after triple therapy with vonoprazan, amoxicillin, and clarithromycin. This case reinforces the notion that non-H. pylori Helicobacter species such as H. suis and H. heilmannii may be involved in the pathogenesis of active gastritis in patients who test negative for H. pylori antibodies.

show abstract

“…According to the ESPGHAN/NASPGHAN guidelines, the current gold standard for H. pylori infection diagnosis in symptomatic children is upper gastrointestinal endoscopy with biopsies for culture, histology, and rapid urease test 7,8 . Nodularity is one of the most common endoscopic findings in H. pylori ‐infected children 9–11 and may be present in 67% of H. pylori ‐infected children, according to Prieto et al 12 Several studies have pointed out the specificity of nodular gastritis for high‐grade H. pylori colonization and chronic active gastritis in H. pylori‐ infected children 13,14 . The presence of lymphoid aggregates and lymphoid follicles is frequent in H. pylori ‐infected children due to the immunological response in chronic gastritis 9,10,15,16 …”

Section: Introductionmentioning

confidence: 99%

Time trend prevalence of helicobacter pylori infection and endoscopic findings in symptomatic children in Portugal: A retrospective study based on three time points in 2009, 2014, and 2019

et al. 2023

View full text Add to dashboard Cite

Background: Helicobacter pylori infection acquisition occurs mainly in childhood and may be a critical factor in developing long-term complications. In contrast to other developed countries, previous studies have reported a relatively high H. pylori infection prevalence in Portugal, both in children and adults. However, there are no recent data concerning pediatric population. Materials and Methods:We performed a retrospective observational study concerning an 11 years period (2009, 2014, 2019), that included patients under 18 years old who underwent upper endoscopy at a pediatric tertiary center. Demographic, clinicalpathological, and microbiological data were collected. Results:Four hundred and sixty one children were included. The average age was 11.7 ± 4.4 years. In total, H. pylori infection was confirmed in 37.3% of cases (histology and/or culture) and a decreasing infection trend was observed (p = .027). The most common indication for endoscopy was abdominal pain, which was a good predictor of infection. Antral nodularity was present in 72.2% of the infected children (p < .001).In the oldest age groups, moderate/severe chronic inflammation, H. pylori density and lymphoid aggregates/follicles were positive predictors for the presence of antral nodularity. For all ages, the presence of antral nodularity, neutrophilic activity in the antrum and corpus and lymphoid follicles/aggregates in the antrum were positive predictors for the presence of H. pylori infection. Among the 139 strains tested for antibiotic susceptibility, 48.9% were susceptible to all tested antibiotics. Resistance to clarithromycin, metronidazole, and both was detected in 23.0%, 12.9%, and 6.5% of the strains, respectively; furthermore, resistance to ciprofloxacin and to amoxicillin was observed in 5.0% and 1.4% of the strains, respectively. Conclusions:The present study reports (for the first time in Portugal) a significant decreasing trend in the prevalence of pediatric H. pylori infection, although it remains relatively high compared to the recently reported prevalence in other South European countries. We confirmed a previously recognized positive association of How to cite this article:

show abstract

Endoscopic findings of Helicobacter pylori gastritis in children and young adults based on the Kyoto classification of gastritis and age‐associated changes

Cited by 15 publications

References 17 publications

Can Saccharomyces boulardii treat and eradicate Helicobacter pylori among children instead of bismuth?

Can Saccharomyces boulardii treat and eradicate Helicobacter pylori among children instead of bismuth?

Helicobacter suis-Associated Gastritis Mimicking Conventional H. pylori-Associated Atrophic Gastritis

Time trend prevalence of helicobacter pylori infection and endoscopic findings in symptomatic children in Portugal: A retrospective study based on three time points in 2009, 2014, and 2019

Contact Info

Product

Resources

About