2018
DOI: 10.21037/tgh.2018.10.09
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Endoscopic management of perforations, leaks and fistulas

Abstract: The endoscopic management armamentarium of gastrointestinal disruptions including perforations, leaks, and fistulas has slowly but steadily broadened in recent years. Previously limited to surgical or conservative medical management, innovations in advanced endoscopic techniques like natural orifice transluminal endoscopic surgery (NOTES) have paved the path towards development of endoscopic closure techniques. Early recognition of a gastrointestinal defect is the most important independent variable in determi… Show more

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Cited by 40 publications
(52 citation statements)
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References 107 publications
(117 reference statements)
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“…Although the treatment of our patient was successful and the chosen technique appropriate, other options with different profiles in terms of safety, cost, and evidence are available; namely, but not limited to, endo-sponge application, placement of a covered self-expanding metal stent, over-the-scope clip (OTSC) positioning, and fibrin glue injection [17]. OTSC has a limited role in large perforations.…”
Section: Discussionmentioning
confidence: 99%
“…Although the treatment of our patient was successful and the chosen technique appropriate, other options with different profiles in terms of safety, cost, and evidence are available; namely, but not limited to, endo-sponge application, placement of a covered self-expanding metal stent, over-the-scope clip (OTSC) positioning, and fibrin glue injection [17]. OTSC has a limited role in large perforations.…”
Section: Discussionmentioning
confidence: 99%
“…Those stents are the most used in upper gastrointestinal defects, being a successful treatment on perforations and fistulas on esophagus in more of 90% of the cases. 8 This alternative treatment was chosen because of the inaccessibility of the abdomen. Nevertheless, it must be kept in mind all the consequences that a procedure can carry.…”
Section: Discussionmentioning
confidence: 99%
“…18 With early recognition, small perforations can be successfully treated with various endoscopic methods. 19 Two premixed injection solutions are currently approved by the U.S. Food and Drug Administration. The…”
Section: Agents For Submucosal Injectionmentioning
confidence: 99%