Endoscopic polypectomy of a large duodenal carcinoid

Alberti-Flor, Juan J.; Hernandez, Moises E.; Ferrer, Jose P.

doi:10.1016/s0016-5107(93)70288-6

Cited by 4 publications

(2 citation statements)

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“…Most reports state that duodenal neuroendocrine tumor can be treated by endoscopic excision, when the diameter is less than 10 mm and there is no invasion of the muscularis propria [1]. On the other hand, others have shown that the features associated with metastatic risk are a diameter greater than 2 cm [2], and those with duodenal neuroendocrine tumor with a diameter larger than 10 mm can be successfully treated by endoscopic procedure [3,4]. Therefore, it is controversial whether endoscopic treatment is appropriate for duodenal neuroendocrine tumor larger than 10 mm in diameter.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic resection of duodenal bulb neuroendocrine tumor larger than 10 mm in diameter

et al. 2011

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BackgroundEndoscopic treatment for duodenal bulb neuroendocrine tumor larger than 10 mm is still controversial. This report presents four cases successfully treated with endosonography (EUS)-assisted endoscopic mucosal resection (EMR) procedure for duodenal bulb neuroendocrine tumor larger than 10 mm in diameter.MethodsThe case series of four patients diagnosed with neuroendocrine tumor from 2003 to 2008 were reviewed. EUS demonstrated well-defined hypoechoic tumors confined to the submucosal hyperechoic layer and the underlying hypoechoic muscularis propria was intact in all four patients. EMR were planned and performed for the duodenal bulb neuroendocrine tumors larger than 10 mm.ResultsEn bloc resections with tumor free lateral and basal margins were accomplished using an endoscopic diathermic snare with forward-viewing instruments without any complications. Neither residual duodenal neuroendocrine tumors nor metastatic lesions were detected during the observation period ranging 19 to 78 monthsConclusionDuodenal bulb neuroendocrine, larger than 10 mm in diameter, can be treated by endoscopic procedure, after confirming that the tumor confined to the submucosal layer in EUS examination, and no lymph node involvement by abdominal CT and US.

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Section: Introductionmentioning

confidence: 99%

Endoscopic resection of duodenal bulb neuroendocrine tumor larger than 10 mm in diameter

et al. 2011

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“…With the widespread use of gastrointestinal endoscopy, these tumors are being increasingly recognized. Although several papers have reported the successful treatment of these tumors by endoscopic mucosal resection (EMR) after submucosal hypertonic saline-epinephrine (HSE) injection [2][3][4], the most effective treatment for duodenal carcinoid tumors remains debatable. Because carcinoid tumors of the gastrointestinal tract tend to spread to the submucosal layer even during early stages of the disease, the possibility of tumor seeding in the vertical margin of the tumor cannot be eliminated by conventional EMR.…”

Section: Introductionmentioning

confidence: 99%