“…The standard treatment is balloon dilation, pyloroplasty, or occasionally surgical distal gastrectomy [1]. Peroral endoscopic pyloromyotomy (POP) has been used to improve gastric emptying in selected patients with refractory gastroparesis due to diabetes [2,3] or with gastric outlet obstruction following esophagectomy [4]. To the best of our knowledge, this is the first case in which POP was used to treat PPS.…”