Endoscopic Resection of Sinonasal Cancers With and Without Craniotomy

Hanna, Ehab Y.; DeMonte, Franco; Ibrahim, Samer; Roberts, Dianna B.; Levine, Nicholas B.; Kupferman, Michael E.

doi:10.1001/archoto.2009.173

Cited by 335 publications

(286 citation statements)

References 20 publications

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“…We performed orbital exenteration (7) and CFR (4) when there was significant periorbit and dural invasion, respectively. As opposed to other series [7,10], we do not support low threshold for performing CFR because we argue that the high rate of surgical complication and morbidity overpass the survival rates improvements.…”

Section: Discussioncontrasting

confidence: 78%

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Bernardo¹,

Ferreira²,

Silva³

et al. 2013

IJOHNS

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Introduction and Objectives: Sinonasal tumours represent only 3% of all head and neck cancers. Adenocarcinoma is the second most frequent histopathology type. Hardwood exposure has been considered a risk factor. Sinonasal adenocarcinoma grows silently which leads to a late diagnosis and low survival rates. The aim of this study was to present our experience in the management of the patients with sinonasal adenocarcinoma. Method: Retrospective medical records review of patients with sinonasal adenocarcinomas (1974 to 2009). Results: From 301 patients with sinonasal tumors, 67 had histology of adenocarcinoma. Patient average age was 60.1 ± 11.1 years (30 -84 years). 83.6% were man. 65.7% had history of working with wood. 70.1% of the patients had advance disease. The most common treatment strategy was external surgery (lateral rhinotomy (47.8%), sublabial (17.9%) or cranio-facial resection (6%)) or endoscopic approaches with postoperative radiotherapy. The 3 and 5 years overall survival rate were 60% and 49%, respectively. Conclusions: Our group study showed similar epidemiologic characteristics than other series. We confirmed sinonasal adenocarcinomas tendency to late diagnosis and wood dust exposure relation. In our experience, the limited surgical treatment (without craniofacial resection) and postoperative radiotherapy has good survival rates results, similar to other departments who consider the craniofacial resection as the standard treatment.

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Section: Discussioncontrasting

confidence: 78%

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Bernardo¹,

Ferreira²,

Silva³

et al. 2013

IJOHNS

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“…Interestingly, while positive margin status has been shown to be adverse in sinonasal cancer resection, surgery with widely negative margins isn't clearly better than more conservative ones, as long as clinically negative margins are achieved. Further, although no large, or randomized, studies have been performed for comparison, piecemeal resection via endoscopic approaches appears to be as effective as en bloc resection [3,29]. Precision radiotherapy, such as intensity modulated radiation therapy and gamma knife have improved treatment and lessened morbidity, particularly for those patients with tumors adjacent to the orbits, skull base, and brain.…”

Section: Treatment and Prognosismentioning

confidence: 99%

Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Papillomavirus

Lewis

2016

Head and Neck Pathol

110

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The sinonasal tract is one of the least frequent sites for squamous cell carcinoma in the head and neck. However, it is still a complex tumor type for pathologists because there are numerous histologic variants with unusual morphologic features, several non-squamous carcinomas in the differential diagnosis that can have similar morphology and even squamous differentiation, and because of the increasing recognition of human papillomavirus (HPV) in a subset of the tumors. In addition, the unique and complex anatomy of the sinonasal tract can make proper staging and management of patients' tumors quite challenging. This article reviews sinonasal tract squamous cell carcinoma in depth and provides the latest data on Schneiderian papillomas and HPV in their pathogenesis.

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“…Средний период наблюдения составил 37 мес. Локального контроля удалось достичь у 85% паци-ентов, при этом уровень 5-и 10-летней выживае-мости в зависимости от болезни составил 87 и 80% соответственно [20]. Согласно Европейскому доку-Рис.…”

Section: Discussionunclassified

Clinical Significance of Transnasal Endoscopic Surgery in the Treatment of Children With Localized Parameningeal Sarcomas

et al. 2017

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ОБОСНОВАНИЕСаркомы костей и мягких тканей чаще встречают-ся у пациентов моложе 21 года. Рабдомиосаркома (РМС) -основной гистологический тип сарком дет-ского возраста, который составляет до 6% всех опу-холей у пациентов младше 15 лет. РМС чаще (36%) локализуется в органах головы и шеи. По лока-лизации саркомы головы и шеи разделяют на два анатомических региона -пара-и непараменин-геальный, различающиеся прогнозом заболева-ния. К параменингеальной локализации относятся опухоли, расположенные в полости носа, носоглот-ке, околоносовых пазухах, среднем ухе, височной кости, а также в подвисочной и крылонебной ямках [1]. Другие морфологические варианты сарком мягких тканей параменингеальной локализации и саркомы костей основания черепа составляют не более 1% среди всех злокачественных опухолей детского возраста. Лечебные подходы основаны на проведении полихимиотерапии (ПХТ) в предоперационном периоде и лучевой терапии при чувствительности опухоли к лучевому воздействию.Результаты международных исследовательских групп IRS 1 и COG 2 убедительно доказали влияние на исход лечения детей с РМС таких независимых факторов, как локализация первичной опухоли, размер, инвазия в соседние органы и ткани, а так-же метастатическое поражение региональных лим-фатических узлов и наличие отдаленных метастазов

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Endoscopic Resection of Sinonasal Cancers With and Without Craniotomy

Cited by 335 publications

References 20 publications

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Sinonasal Adenocarcinoma—Experience of an Oncology Center

Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Papillomavirus

Clinical Significance of Transnasal Endoscopic Surgery in the Treatment of Children With Localized Parameningeal Sarcomas

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