Endoscopic retrograde appendicitis therapy: a pilot minimally invasive technique (with videos)

Liu, Bing-Rong; Song, Ji‐Tao; Han, Fei; Li, Hui; Jia, Yin

doi:10.1016/j.gie.2012.05.029

Cited by 60 publications

(45 citation statements)

References 13 publications

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“…In 2006, Liu et al reported the successful use of an endoscopic retrograde cholangiopancreatography (ERCP) catheter to aspirate pus and wash away fecaliths from the appendix in a patient with acute appendicitis [7]. Recently, Liu et al and Li et al applied a similar ERCP technique, called endoscopic retrograde appendicitis therapy (ERAT), to treat acute uncomplicated appendicitis [8,9]. In their study, the researchers also found that the ERAT technique may have some value in the diagnosis of acute appendicitis, particularly for those whom conventional imaging was inconclusive.…”

Section: Introductionmentioning

confidence: 99%

Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis

Mao

Yang

et al. 2018

Z Gastroenterol

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Section: Introductionmentioning

confidence: 99%

Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis

Mao

Yang

et al. 2018

Z Gastroenterol

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“…With the development of immunology and microbiology, people gradually realized that appendix plays a crucial role in intestine mucosal immunity and in maintaining the balance of intestinal flora [ 21 - 23 ]. To reduce the side effect and achieve minimally invasive treatment, in 2009, we established a new therapeutic method-endoscopic retrograde appendicitis therapy (ERAT) for acute uncomplicated appendicitis [ 24 ]. There are 5 steps in ERAT: (1) endoscopic appendiceal intubation; (2) appendiceal decompression; (3) retrograde appendicography; (4) stent drainage; and (5) cleansing the appendiceal lumen [ 24 ].…”

Section: Introductionmentioning

confidence: 99%

“…To reduce the side effect and achieve minimally invasive treatment, in 2009, we established a new therapeutic method-endoscopic retrograde appendicitis therapy (ERAT) for acute uncomplicated appendicitis [ 24 ]. There are 5 steps in ERAT: (1) endoscopic appendiceal intubation; (2) appendiceal decompression; (3) retrograde appendicography; (4) stent drainage; and (5) cleansing the appendiceal lumen [ 24 ]. Our previous study demonstrated that effective rate of ERAT was up to 97%, with few complications [ 25 ].…”

Section: Introductionmentioning

confidence: 99%

The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis

et al. 2017

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This study was conducted to evaluate the immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute suppurative appendicitis and to determine whether TLR4/MYD88/NF-κB signaling pathway was activated in this process. 48 rabbits were assigned into 4 groups: group I, the mimic endoscopic retrograde appendicitis therapy group; group II, the appendectomy group; group III, the model group; and group IV, the blank group. White blood cells decreased, while levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, interleukin-4, and interleukin-10 increased on the 2nd day in group I and II. IgA in feces decreased at 2 weeks, while fecal microbiota changed at 2 and 4 weeks after appendectomy. CD8+ cells in appendix of group I increased within 8 weeks. Upregulated expression of TLR4, MYD88, and nuclear NF-κB were detected on the 2nd day in group I and II. Mimic endoscopic retrograde appendicitis therapy and appendectomy are effective ways for acute suppurative appendicitis. Mimic endoscopic retrograde appendicitis therapy was more preferable due to its advantage in maintaining intestinal immune function. TLR4/MYD88/NF-κB signaling pathway was activated in acute phase of appendicitis.

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“…Colonoscopic appendicography has been reported as a useful technique in differentiate indistinct abdominal symptoms [3]. Endoscopic retrograde appendicitis therapy (ERAT) was first reported in 2012 as a new procedure for management of acute appendicitis [4]. The first step in ERAT is endoscopic retrograde appendicography (ERA) performed to confirm the diagnosis of acute appendicitis.…”

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confidence: 99%

Endoscopic retrograde appendicography: an effective diagnostic method for acute appendicitis

Hai

Ullah

et al. 2020

Preprint

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Background and Aim: Appendicography had been used in the diagnosis of chronic appendicitis. To our knowledge, the role of endoscopic retrograde appendicography for the diagnosis of acute appendicitis remains unknown. The aim of this study was to evaluate the role of endoscopic retrograde appendicography for the diagnosis of acute appendicitis.Patients and Method: Patients with suspected acute appendicitis between December 2013 and November 2015 at Second Affiliated Hospital of Harbin Medical University underwent endoscopic retrograde appendicography. The findings and complication were analyzed retrospectively.Results: Thirty-three patients (20 men and 13 women, average age 44 ± 18 years) with suspected acute appendicitis were studied. Acute appendicitis was ruled out by normal endoscopic retrograde appendicography in 24% and confirmed in 69.6% (23). In 2 patients (8%) appendiceal orifice cannulation failed. Colonoscopic findings in acute appendicitis were mucosal hyperemia and edema of appendiceal orifice (83%), outpouring of pus from the appendiceal orifice (74%), and swollen cecal mucosa (61%). Appendicograpic findings were either normal or in acute disease showed diffuse lumenal dilation (diameter: 0.8 ± 0.4 mm), partial stenosis (43%), stiffness or inflexibility (87%) and filling defects (22%). There were no complications during or after follow-up for a median of 13 months (IQR: 9-24 months).Conclusions: Endoscopic retrograde appendicography appears to be a reliable and safe method to confirm or exclude the diagnosis of acute appendicitis and prevent unnecessary appendectomy.

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Endoscopic retrograde appendicitis therapy: a pilot minimally invasive technique (with videos)

Cited by 60 publications

References 13 publications

Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis

Endoscopic retrograde appendicitis techniques for the treatment of patients with acute appendicitis

The immune impact of mimic endoscopic retrograde appendicitis therapy and appendectomy on rabbits of acute appendicitis

Endoscopic retrograde appendicography: an effective diagnostic method for acute appendicitis

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