Endoscopic sinus surgery: Outcome in 155 cases

Matthews, Brian L.; Smith, Lee E.; Jones, Robert; Miller, C. K.; Brookschmidt, Joni K.

doi:10.1177/019459989110400214

Cited by 83 publications

(54 citation statements)

References 5 publications

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“…Headache and Nasal obstruction responded the best among the symptoms. These findings are consistent with those of the other series [7][8][9][10][11][12][13][14][15][16]. 91 patients in the present study had bilateral OMU blocked, thus reemphasizing the role of OMU in the pathophysiology of CRS, as mentioned by Messerklinger [3].…”

Section: Discussionsupporting

confidence: 94%

“…In inexperienced hands, the major complications associated with FESS can include intracerebral haemorrhage, CSF leak, diplopia, blindness, intracranial penetration, meningitis and severe haemorrhage. Our complication rates are the same as reported by other authors [7][8][9][10][11][12][13][14][15][16]. FESS is a very effective and safe procedure when performed by surgeons experienced in the technique.…”

Section: Discussionsupporting

confidence: 87%

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Retrospective Analysis of the Effectiveness of Functional Endoscopic Sinus Surgery in the Treatment of Adult Chronic Rhinisinusitis Refractory to Medical Treatment

Shivakumar

Sambandan

2011

Indian J Otolaryngol Head Neck Surg

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Chronic rhinosinusitis (CRS) is a common disease that restricts the quality of life of millions of involved patients. The aim of the study was to evaluate how functional endoscopic sinus surgery (FESS) modifies patients symptom profile and to also confirm that FESS is the modality of treatment in patients with refractory CRS. The study was retrospective analysis. 105 patients with symptoms of CRS were included in the study (between August 2006 to July 2009). Patients were assessed for CRS symptoms preoperatively and postoperatively using grading symptoms. Statistical analysis using Chi square test. Leading symptom of CRS was nasal obstruction followed by headache. Furthermore patients reported of anosmia, facial pressure, postnasal drip, purulent nasal discharge, halitosis, dental pain, cough, earache. None of the patients had fever as their complaint. After a postoperative followup of 6 months there was improvement in the symptoms. All minor symptoms had 100% improvement. Nasal obstruction responded best, next followed by (all symptoms P value <0.001). An overall improvement of 86.66% was recorded. The restriction of quality of life in patients with CRS is mainly caused by these symptoms, which can be improved in excellent fashion by FESS in majority of the patients.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 87%

Retrospective Analysis of the Effectiveness of Functional Endoscopic Sinus Surgery in the Treatment of Adult Chronic Rhinisinusitis Refractory to Medical Treatment

Shivakumar

Sambandan

2011

Indian J Otolaryngol Head Neck Surg

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“…The efficacy of MMC, which remained limited in clinical studies, can be enhanced by using two doses, obviating the need for revision surgery after ESS, which was reported to vary between 7.6 and 38% [2,27] in various studies and increasing the quality of life in patients. Actually, in a clinical study carried out at a date when we obtained our initial results, it was reported that MMC administered twice, namely intraoperatively and in early post-op period, is efficacious and reliable [28].…”

Section: Discussionmentioning

confidence: 99%

The effects of repetitious topical use of mitomycin C on antrostomy patency in maxillary antrostomy created rabbit model

Kavuzlu

Arslan

Taştan

et al. 2011

Eur Arch Otorhinolaryngol

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The aim of our study was to investigate the effect of the topical use of mitomycin C (MMC) intraoperatively in single dose and intra-postoperatively in two doses on the narrowing of antrostomy in maxillary rabbit sinus antrostomies created experimentally. And also to determine the local and systemic side effects of topical MMC. With this objective, 0.6 mg/ml MMC was used to the first group at single dose and to the second group intraoperatively and on third day postoperatively in two doses topically for 5 min. After 8 weeks, although the mean area of antrostomy was larger than that in the control side in the first group, which received single dose MMC, the difference was not statistically significant (p = 0.287). The second group received two doses, and the antrostomy areas were found to be significantly larger than the controls (p = 0.05). Overall, the sides that received MMC were significantly larger (p = 0.029). From the point of histopathological examination of the tissue, it was seen that two-dose MMC increased the edema indicating inflammation and antrostomy resolved with normal respiratory tract epithelium. It was shown by measuring the blood values that nephrotoxic and myelosupressant effect of MMC occurring in systemic use did not occur with single or double dose topical use. Our results demonstrate that even if the number of cases was low, two doses of topical MMC usage prevent the narrowing of antrostomy while single dose MMC does not. And two-dose topical MMC usage does not have local and systemic side effects.

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“…15 In the extended study population, the number of patients who underwent revision surgery (7.4%), with an average follow-up of 1.4 years, is comparable to that seen in OR-based BSD and OR-based ESS. 8,[16][17][18] This is particularly encouraging, as most surgeons were performing their first office-based cases within this study. Revision procedures on 2 patients were performed in an office setting, suggesting that for some recalcitrant patients, repeated office-based procedures may obviate the need for an OR-based procedure.…”

Section: Discussionmentioning

confidence: 72%