Endoscopic ultrasound-guided fine-needle aspiration and Trucut biopsy in thoracic lesions: When tissue is the issue

Storch, Ian; Shah, Mudasir Ahmad; Thurer, Richard; Donna, Elio; Ribeiro, Afonso

doi:10.1007/s00464-007-9374-x

Cited by 53 publications

(28 citation statements)

References 21 publications

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“…In our study, we have been able to obtain an adequate sample for histological evaluation in all lesions but one, with an excellent sample, providing real tissue architecture in 77 % of cases. This was associated with a very high diagnostic accuracy (95.4 %), improving the previously reported diagnostic yield of standard cytology (5-7) and other biopsy needles (44)(45)(46). As a relevant issue, these data were obtained after performing only one pass into the target lesion.…”

Section: Discussionmentioning

confidence: 67%

“…Although biopsy with quick-Core ® needle has no (1) clear advantage over EUS-FNA in terms of overall sensitivity and diagnostic accuracy, it does provide with a more specific diagnosis in selected cases with less needle passes (29,37,44). A combination of EUS-biopsy with quickCore ® needle and EUS-FNA has shown a higher overall diagnostic yield than any of the two needles alone (45)(46)(47). The overall accuracy of EUS-biopsy in these later studies ranges from 61 % to 84 %.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Iglesias‐García

Abdulkader

Lariño‐Noia

et al. 2014

Rev. esp. enferm. dig.

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Background: Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is an accurate technique for sampling intraintestinal and extraintestinal lesions. However, cytology possesses certain limitations, which may be overcome if histological specimens are provided to the pathologist.Aim: The aim of the study was to evaluate the accuracy of a newly developed 19G histology needle.Methods: Retrospective analysis of a prospectively collected data base including patients who underwent EUS-guided biopsy with the 19G ProCore TM histology needle for the evaluation of intraintestinal or extraintestinal lesions. Samples were obtained after one needle pass, recovered into ThinPrep ® and processed for histological analysis. Results were compared to the gold standard of surgical histopathology, or global pathological, clinical and radiological assessment, and follow-up in non-operated cases. Results are shown as mean ± SD. Percentage of optimal samples for histological evaluation and the overall diagnostic accuracy were evaluated.Results: 87 patients (mean age 62.9 years, range 25-88 years, 36 woman) were included. Lesions mean size was 41.6 ± 21.3 mm. 66 lesions (75.9 %) were considered as malignant and 21 (24.1 %) as benign. EUS-guided biopsy was feasible in all cases (100 %). Sample quality was adequate for histological assessment in 82 lesions (94.2 %). In the remaining cases the sample was adequate for cell-block evaluation. Sensitivity, specificity, PPV, NPV, and overall accuracy for malignancy were 93.4 %, 100 %, 100 %, 84 %, and 95.4 %, respectively. There were no complications related to the procedure. Conclusion:The EUS-guided biopsy with the 19G histology needle provides with an optimal core sample for histological evaluation allowing a high histopathologic diagnostic accuracy.

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Section: Discussionmentioning

confidence: 67%

Section: Discussionmentioning

confidence: 99%

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Iglesias‐García

Abdulkader

Lariño‐Noia

et al. 2014

Rev. esp. enferm. dig.

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“…29 More recently, combination of EUS-biopsy with Quick-Core needle and EUS-FNA has shown a higher overall diagnostic yield compared with when each technique is performed alone. [40][41][42] The overall accuracy of EUS-biopsy in these latter studies ranges between 61% and 84%. In our study, using the EUS-FNB needle, a sample adequate for full histological evaluation was obtained in about 90% of the evaluated lesions.…”

Section: Discussionmentioning

confidence: 98%

Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study

Iglesias‐García

Poley

Larghi

et al. 2011

Gastrointestinal Endoscopy

285

311

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“…4,9 Most studies that have compared FNA to TCB specimens have shown that TCB is at least as accurate as FNA and the two methods are often complimentary with an increased overall combined diagnostic accuracy. 6,[9][10][11][12][13][14][15] The goal of this study was to compare EUS-FNA and TCB specimens to determine the performance characteristics of both EUS collection techniques in routine clinical practice within our institution.…”

mentioning

confidence: 99%

Comparison of EUS‐guided FNA and Trucut biopsy for diagnosing and staging abdominal and mediastinal neoplasms

Kipp¹,

Pereira²,

Souza³

et al. 2009

Diagnostic Cytopathology

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The objective of this study was to evaluate endoscopic ultrasound Trucut biopsy (TCB) specimens and compare these findings to fine needle aspiration (FNA) specimens for the diagnosis of neoplasia. FNA and TCB specimens were reviewed in blinded fashion by a cytopathologist from patients (N = 93) who had EUS-guided FNA and TCB specimens collected between July 2000 and January 2005. Specimens were categorized as nondiagnostic, negative, suspicious for stromal neoplasm, suspicious for malignancy, positive for stromal neoplasm, or positive for malignancy. Standard final diagnosis based on clinical and/or pathologic follow-up was available for 86 of 93 patients. The final diagnoses comprised malignancy (n = 55), stromal neoplasm (n = 19), and benign findings (n = 12). The combination of FNA and TCB results combined were significantly (P < 0.001) more sensitive that FNA alone for the detection of both malignancy (78% vs. 55%) and stromal neoplasia (79% vs. 19%) without a significant change in overall specificity (92% vs. 100%, P = 1.00). A positive FNA specimen with a negative/nondiagnostic TCB result was established in seven patients with malignancy. A positive TCB diagnosis with a negative/nondiagnostic FNA result was noted in five patients with malignancy. A suspicious FNA result was upgraded to positive in conjunction with TCB specimen evaluation in eight patients with malignancy. The results of this study suggest that TCB is a useful adjunctive technique when used in tandem with FNA for malignancy and stromal neoplasia detection. Additional data are needed to firmly establish practice guidelines for the use of EUS-guided TCB specimens in clinical practice.

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Endoscopic ultrasound-guided fine-needle aspiration and Trucut biopsy in thoracic lesions: When tissue is the issue

Abstract: The combination of TCB and FNA is superior to FNA alone. EUS-guided TCB should be considered in patients with benign disorders of the mediastinum when other modalities fail to yield a diagnosis.

Cited by 53 publications

References 21 publications

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Feasibility and yield of a new EUS histology needle: results from a multicenter, pooled, cohort study

Comparison of EUS‐guided FNA and Trucut biopsy for diagnosing and staging abdominal and mediastinal neoplasms

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