Endothelial Keratoplasty: Prospective, Randomized, Masked Clinical Trial Comparing an Injector With Forceps for Tissue Insertion

Outcomes After Descemet Stripping Automated Endothelial Keratoplasty in Patients With Glaucoma Drainage Devices

“…Endothelial cell loss within 6 to 12 months after any EK procedure, including DMEK, has been reported to be anywhere from 20% to 50%. [7][8][9][10][11][12][13][14][20][21][22] In the few studies with follow-up of 1 year or more, it seemed that the most substantial amount of endothelial cell loss after DSEK occurred in the initial postoperative period, typically within 6 months. 12,13,15,16,23 The rate then slowed and plateaued.…”

Descemet stripping automated endothelial keratoplasty

“…The mean endothelial cell loss, including that in the rebubbled eyes, was 41.2% and 31.4% at 12 months in the Tan EndoGlide and EndoSerter groups, respectively. [35]…”

“…[3536373839404142434445464748495051525354555657585960616263646566676869707172] Figs. 1 and 2 show the postoperative outcomes after DSAEK and ultrathin DSAEK, respectively.…”

“…Analysis of the available studies suggests endothelial cell loss in the range of 25%–61% at 3-year follow-up. [1035447273] At 5 years follow-up, it has been reported to be around 51.9%. [52]…”

Evolving indications for Descemetʼs stripping automated endothelial keratoplasty

“…We believe that the increased versatility of DSAEK over DMEK in these complex keratoplasty settings lies in the nature of the procedures themselves. DSAEK offers a wide range of graft insertion techniques including forcep insertion, tissue glides, inserter devices and suture pull through, several of which have been validated in large series [15][16][17][18][19][20][21][22][23][24]. Each of these techniques offers potential advantages in the management of complex endothelial keratoplasty.…”