Endothelium functional state and evaluation of tissue hypoxia in patients at the moment of the transitorial ischemic attacks development

Abstract

Purpose. To study microcirculatory, metabolic disturbances and the possibility of their correction in patients with transient ischemic attacks (TIA) when used in the complex treatment of laser hemotherapy (LH). Material and methods. We studied the vasomotor function of the endothelium, the parameters of carbohydrate-energy metabolism and lipid peroxidation (LPO) in the blood. Results. Endothelial dysfunction, increased lactate/ pyruvate ratio, increased LPO, low activity of superoxidedismutase were established. The complex treatment improves microcirculatory and metabolic parameters. Conclusions. It is recommended to include LH in the complex treatment of patients with TIA.