Endovascular Treatment of Descending Thoracic Aortic Aneurysms

Coppi, Gilberto; Gennai, Stefano; Silingardi, Roberto; Benassi, F.; Cataldi, Valentina

doi:10.5772/54692

Cited by 2 publications

(2 citation statements)

References 52 publications

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“…Some methodologies have been developed for the analysis of ciclopirox olamine in topical solutions, creams and raw materials, among them gas chromatography 5, high‐performance liquid chromatography 6–8 and capillary electrophoresis 9,10. However, because of the labourious and generally time‐consuming procedures required, many of these methods are not appropriate for rapid and simple quality control to support pharmaceutical production processes.…”

Section: Introductionmentioning

confidence: 99%

Fast Determination of Ciclopirox in Pharmaceutical Products by Amperometry in Flow and Batch Injection Systems

2012

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Amperometry coupled to flow injection analysis (FIA) and to batch injection analysis (BIA) was used for the rapid and precise quantification of ciclopirox olamine in pharmaceutical products. The favourable hydrodynamic conditions provided by both techniques allowed a very high throughput (more than 300 injections per hour) with good linear range (2.0–200 µmol L−1) and low limits of detection (below 1.0 µmol L−1). The results obtained were compared with titration recommended by the American Pharmacopoeia and also using capillary electrophoresis. Good agreement between all results were achieved, demonstrating the good performance of amperometry combined with FIA and BIA.

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Section: Introductionmentioning

confidence: 99%

Fast Determination of Ciclopirox in Pharmaceutical Products by Amperometry in Flow and Batch Injection Systems

2012

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“…1. Some methods have been described in the literature for the quantification of ciclopirox olamine in topical solutions and in raw materials, among them high-performance liquid chromatography [5][6][7], gas chromatography [8], MEKC [9], and polarography [10]. Some of these reported methods require time-consuming sample preparation or expensive instrumentation.…”

Section: Introductionmentioning

confidence: 99%

Determination of ciclopirox olamine in pharmaceutical products by capillary electrophoresis with capacitively coupled contactless conductivity detection

2011

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This paper describes the determination of ciclopirox olamine in pharmaceutical formulations using capillary electrophoresis with capacitively coupled contactless conductivity detection. In an alkaline medium, ciclopirox olamine is converted into an anionic species and its detection is possible in capillary electrophoresis with capacitively coupled contactless conductivity detection without an electroosmotic flow modifier, because it is a low-mobility species. A linear working range from 2.64 to 264 μg/mL in sodium hydroxide electrolyte as well as low detection limit (0.39 μg/mL) and a good repeatability (RSD = 3.4% for 264 μg/mL ciclopirox solution (n = 10)) were achieved. It was also possible to determine olamine in its cationic form when acetic acid was used as the electrolyte solution. The results obtained include a linear range from 26.4 to 184.8 μg/mL and a detection limit of 2.6 μg/mL olamine. The proposed methods were applied to the analysis of commercial pharmaceutical products and the results were compared with the values indicated by the manufacturer as well as those obtained using a titrimetric method recommended by American Pharmacopoeia.

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Endovascular Treatment of Descending Thoracic Aortic Aneurysms

Cited by 2 publications

References 52 publications

Fast Determination of Ciclopirox in Pharmaceutical Products by Amperometry in Flow and Batch Injection Systems

Fast Determination of Ciclopirox in Pharmaceutical Products by Amperometry in Flow and Batch Injection Systems

Determination of ciclopirox olamine in pharmaceutical products by capillary electrophoresis with capacitively coupled contactless conductivity detection

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