Energization of Vacuolar Transport in Plant Cells and Its Significance Under Stress

Seidel, Thorsten; Siek, Michèle; Marg, Berenice; Dietz, Karl‐Josef

doi:10.1016/b978-0-12-407696-9.00002-6

Cited by 27 publications

(19 citation statements)

References 440 publications

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“…(ii) The activity and hence function of several HM transporters localized to the tonoplast are linked to the establishment of electrical membrane potential and proton motive force (Seidel et al . ). Thus, it may be hypothesized that the vacuolar H + ‐pumps adapted concomitantly with the elevated expression of transporters such as in HM hyperaccumulator plants or conditionally in non‐hyperaccumulators.…”

Section: Discussionmentioning

confidence: 99%

“…(i) In vivo functional evidence needs to be complemented by detailed biochemical characterization in relation to maximal activity, affinity, competitiveness, specificity, directionality and energetic coupling. (ii) The activity and hence function of several HM transporters localized to the tonoplast are linked to the establishment of electrical membrane potential and proton motive force (Seidel et al 2013). Thus, it may be hypothesized that the vacuolar H + -pumps adapted concomitantly with the elevated expression of transporters such as in HM hyperaccumulator plants or conditionally in non-hyperaccumulators.…”

Section: Discussionmentioning

confidence: 99%

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Vacuolar compartmentalization as indispensable component of heavy metal detoxification in plants

Sharma

Dietz

Mimura

2016

Plant Cell & Environment

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439

169

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Plant cells orchestrate an array of molecular mechanisms for maintaining plasmatic concentrations of essential heavy metal (HM) ions, for example, iron, zinc and copper, within the optimal functional range. In parallel, concentrations of non-essential HMs and metalloids, for example, cadmium, mercury and arsenic, should be kept below their toxicity threshold levels. Vacuolar compartmentalization is central to HM homeostasis. It depends on two vacuolar pumps (V-ATPase and V-PPase) and a set of tonoplast transporters, which are directly driven by proton motive force, and primary ATP-dependent pumps. While HM non-hyperaccumulator plants largely sequester toxic HMs in root vacuoles, HM hyperaccumulators usually sequester them in leaf cell vacuoles following efficient long-distance translocation. The distinct strategies evolved as a consequence of organ-specific differences particularly in vacuolar transporters and in addition to distinct features in long-distance transport. Recent molecular and functional characterization of tonoplast HM transporters has advanced our understanding of their contribution to HM homeostasis, tolerance and hyperaccumulation. Another important part of the dynamic vacuolar sequestration syndrome involves enhanced vacuolation. It involves vesicular trafficking in HM detoxification. The present review provides an updated account of molecular aspects that contribute to the vacuolar compartmentalization of HMs.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Vacuolar compartmentalization as indispensable component of heavy metal detoxification in plants

Sharma

Dietz

Mimura

2016

Plant Cell & Environment

Self Cite

439

169

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“…75 GTs are involved in phase II metabolism of atrazine 76 and other herbicides, 77 but they also have key roles in conferring tolerance to other abiotic stresses like cold, drought and salt by modulating anthocyanin accumulation. 78,79 In this study, three DEGs (3532, 5629.48 and 3574) were annotated as GTs, all of which were constitutively elevated in MHR4 plants and their differential regulation co-segregated with flucarbazone resistance in F 3 families ( Table 3).…”

Section: Xenobiotic Response/catabolic Processesmentioning

confidence: 90%

“…The eight ABC transporter subfamilies in plants have diverse roles in physiology, especially involving responses to abiotic and biotic stresses . 78,80 Specifically members of the C subfamily play a critical role in herbicide detoxification 81 -83 and have been invoked in conferring glyphosate resistance in Conyza Canadensis. 84,85 In this study we identified two DEGs (1438 and 4170) annotated as C subfamily ABC transporters.…”

Section: Xenobiotic Response/catabolic Processesmentioning

confidence: 99%

Intensive herbicide use has selected for constitutively elevated levels of stress‐responsive mRNAs and proteins in multiple herbicide‐resistant Avena fatua L

Keith

Burns

Bothner

et al. 2017

Pest Management Science

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“…Similar to the plant vacuole, 32 trypanosome acidocalcisomes contain at least 2 proton pumps, V-H CATPase and V-PPase. 24,25 The V-H CATPase is a multisubunit complex comprising of a V 0 sector that forms the proton pore and a V 1 sector that mediates ATP hydrolysis.…”

Section: Starvation-induced Acidocalcisome Acidification Is V-h C -Atmentioning

confidence: 99%

Acidocalcisome is required for autophagy inTrypanosoma brucei

2014

Autophagy

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target of rapamycin complex 1; polyP, polyphosphate; PPi, pyrophosphate; PtdIns3K, phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol 3-phosphate; RNAi, RNA interference; T. brucei, Trypanosoma brucei; Tbb3, the b3 subunit of adaptor protein-3 complex in Trypanosoma brucei; Tbd, the d subunit of adaptor protein-3 complex in Trypanosoma brucei; TbVMA1, the subunit A of V-H C -ATPase in Trypanosoma brucei; TbVP1, vacuolar pyrophosphatase in Trypanosoma brucei; TbVPH1, the a subunit of V-H C -ATPase in Trypanosoma brucei; TOR, target of rapamycin; V-H C -ATPase, vacuolar-type H C -ATPase; V-PPase, vacuolar pyrophophatase.Lysosomes play important roles in autophagy, not only in autophagosome degradation, but also in autophagy initiation. In Trypanosoma brucei, an early divergent protozoan parasite, we discovered a previously unappreciated function of the acidocalcisome, a lysosome-related organelle characterized by acidic pH and large content of Ca 2C and polyphosphates, in autophagy regulation. Starvation-and chemical-induced autophagy is accompanied with acidocalcisome acidification, and blocking the acidification completely inhibits autophagosome formation. Blocking acidocalcisome biogenesis by depleting the adaptor protein-3 complex, which does not affect lysosome biogenesis or function, also inhibits autophagy. Overall, our results support the role of the acidocalcisome, a conserved organelle from bacteria to human, as a relevant regulator in autophagy.

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Energization of Vacuolar Transport in Plant Cells and Its Significance Under Stress

Cited by 27 publications

References 440 publications

Vacuolar compartmentalization as indispensable component of heavy metal detoxification in plants

Vacuolar compartmentalization as indispensable component of heavy metal detoxification in plants

Intensive herbicide use has selected for constitutively elevated levels of stress‐responsive mRNAs and proteins in multiple herbicide‐resistant Avena fatua L

Acidocalcisome is required for autophagy inTrypanosoma brucei

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