Energy Balance, Ingestive Behavior, and Reproductive Success

Schneider, Jill E.; Watts, Alan G.

doi:10.1016/b978-012532104-4/50009-3

Cited by 15 publications

(21 citation statements)

References 637 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Leptin might act directly on mechanisms that influence hunger motivation and hoarding or indirectly by its well-known effects on energy expenditure and fuel oxidation (21,30,32,33). Our data suggest that food deprivation and leptin treatment had independent, rather than synergistic, effects on hoarding and on 1-h food intake (the drug ϫ metabolic condition interaction was not significant).…”

Section: Discussionmentioning

confidence: 48%

“…Similarly, leptin treatment cannot fully reverse the effects of severe metabolic challenges on aspects of reproductive physiology and behavior (reviewed in Refs. 32,33,39). It is likely that hoarding is directly influenced by a variety of other factors, such as the availability of oxidizable metabolic fuels, other hormones (such as those that rise during pregnancy), photoperiod, and ambient temperature, as has been shown for Siberian hamsters (reviewed in Ref.…”

Section: Discussionmentioning

confidence: 99%

“…Inhibition of reproduction and decreased metabolic rates are two other adaptations correlated with low plasma leptin concentrations (reviewed in Refs. 2,13,32). Two of these responses, hibernation and daily torpor, are incompatible with increased food consumption.…”

Section: Discussionmentioning

confidence: 99%

“…In many species, food deprivation results in decreased plasma concentrations of leptin, increased central release of neuropeptide Y (NPY), and increased food intake relative to that of ad libitum-fed controls (reviewed in Refs. 14,32,33,41). This phenomenon is termed postfast hyperphagia and is common in laboratory animals, such as rats, mice, and monkeys and is also observed in most human beings.…”

mentioning

confidence: 99%

“…Most investigators have measured the amount of food ingested in response to treatment with various hormones, neuropeptides, and metabolic conditions (reviewed in Refs. 1,14,32,33,41), whereas fewer have examined the appetitive aspects of ingestion, such as the approach to food, the consumption of unpalatable substances, or foraging and hoarding (e.g., [3][4][5][6]11). Treatment with putative anorectic hormones, such as the adipocyte protein leptin, decreases the amount of food eaten in a wide variety of species, including chickens (10,12), mice (9,15,18,26), rats (34), Syrian hamsters (39), ground squirrels (25), dogs (20), sheep (16), primates (36), and marsupials (17).…”

mentioning

confidence: 99%

See 4 more Smart Citations

Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters

Buckley

Schneider

2003

American Journal of Physiology-Regulatory, Integrative and Comp

Self Cite

View full text Add to dashboard Cite

. Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters. Am J Physiol Regul Integr Comp Physiol 285: R1021-R1029, 2003. First published May 1, 2003 10.1152 10. /ajpregu.00488.2002satory increases in food intake are commonly observed after a period of food deprivation in many species, including laboratory rats and mice. Thus it is interesting that Syrian hamsters fail to increase food intake after a period of food deprivation, despite a fall in plasma leptin concentrations similar to those seen in food-deprived rats and mice. In previous laboratory studies, food-deprived Syrian hamsters increased the amount of food hoarded. We hypothesized that leptin treatment during food deprivation would attenuate food-deprivation-induced increases in hoarding. Baseline levels of hoarding were bimodally distributed, with no hamsters showing intermediate levels of hoarding. Both high (HH) and low hoarding (LH) hamsters were included in each experimental group. Fifty-six male hamsters were either food deprived or given ad libitum access to food for 48 h. One-half of each group received intraperitoneal injections of leptin (4 mg/kg) or vehicle every 12 h during the food-deprivation period. Within the HH group, the hoarding score increased significantly in food-deprived but not fed hamsters (P Ͻ 0.05). Leptin treatment significantly decreased hoarding in the food-deprived HH hamsters (P Ͻ 0.05). The LH hamsters did not increase hoarding regardless of whether they were food deprived or had ad libitum access to food. These results are consistent with the idea that HH hamsters respond to energetic challenges at least in part by changing their hoarding behavior and that leptin might be one factor that mediates this response. food intake; hunger; ob protein THE PHYSIOLOGICAL CONTROL of ingestive behavior involves both consummatory and appetitive aspects of behavior, and yet most research has focused only on the consummatory aspect. Most investigators have measured the amount of food ingested in response to treatment with various hormones, neuropeptides, and metabolic conditions (reviewed in Refs. 1,14,32,33,41), whereas fewer have examined the appetitive aspects of ingestion, such as the approach to food, the consumption of unpalatable substances, or foraging and hoarding (e.g., 3-6, 11). Treatment with putative anorectic hormones, such as the adipocyte protein leptin, decreases the amount of food eaten in a wide variety of species, including chickens (10, 12), mice (9, 15, 18, 26), rats (34), Syrian hamsters (39), ground squirrels (25), dogs (20), sheep (16), primates (36), and marsupials (17). In many species, food deprivation results in decreased plasma concentrations of leptin, increased central release of neuropeptide Y (NPY), and increased food intake relative to that of ad libitum-fed controls (reviewed in Refs. 14,32,33,41). This phenomenon is termed postfast hyperphagia and is common in laboratory animals, such as rats, mice, and monkeys and is also observed in most human beings.H...

show abstract

Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters

Buckley

Schneider

2003

American Journal of Physiology-Regulatory, Integrative and Comp

Self Cite

View full text Add to dashboard Cite

show abstract

Ovarian hormones and fasting differentially regulate pituitary receptors for estrogen and gonadotropin-releasing hormone in rabbit female

Parillo

Zerani

Maranesi

et al. 2013

Microsc. Res. Tech.

View full text Add to dashboard Cite

To investigate the mechanisms by which caloric restriction affects reproductive function in female rabbits, we measured, in animals intact or ovariectomized (OVX) estrogen-primed and fed ad libitum or fasted for 48 h, the adenohypophysial expression of estrogen receptor-alpha (ESR1) and gonadotropin releasing hormone receptor (GnRHR) and the dynamic secretion of LH following GnRH stimulation. Fasting increased the number of GnRHR-immunoreactive (-IR) cells in intact animals, whereas reduced the density of ESR1-IR cells in OVX rabbits. Estrogen priming decreased the number of ESR1-IR cells in fasted and OVX animals. Ovariectomy increased the number of ESR1-IR cells in fed rabbits, but caused an opposite effect in both fed and fasted animals treated with estrogen. Fasting down regulated the mRNA levels for ESR1 and GnRHR. Estrogen-priming reduced the abundance for ESR1 mRNA in both fed and fasted rabbits, and that for GnRHR in fasted rabbits. Ovariectomy halved ESR1 mRNA levels independently of treatment and feeding condition, whereas increased (P < 001) that for GnRHR in estrogen-primed rabbits. In all rabbits, an LH surge occurred 30 min after GnRH injection but the lowest levels were found in intact fasted rabbits and the highest in fasted, estrogen-primed animals. The LH profile was similar in intact and OVX rabbits and neither fasting nor estrogen priming modified it. In conclusion, fasting differentially modifies the ESR1 and GnRHR expression in the pituitary, depending on the presence of gonadal hormones, indicating complex interactions between metabolic signals and ovarian steroids.

show abstract

Studies of Food Intake: Lessons from Nontraditionally Studied Species

Bartness

Demas

Neurobiology of Food and Fluid Intake

View full text Add to dashboard Cite

Energy Balance, Ingestive Behavior, and Reproductive Success

Cited by 15 publications

References 637 publications

Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters

Food hoarding is increased by food deprivation and decreased by leptin treatment in Syrian hamsters

Ovarian hormones and fasting differentially regulate pituitary receptors for estrogen and gonadotropin-releasing hormone in rabbit female

Studies of Food Intake: Lessons from Nontraditionally Studied Species

Contact Info

Product

Resources

About