Hospitals generate a high amount of carbon dioxide emissions into the atmosphere compared with residential and commercial buildings. Therefore, it is necessary to quantify and identify the CO 2 emissions derived from energy consumption in hospitals, studying their relationship with functional variables. The aim of this article is to analyze the CO 2 emissions derived from the hospital energy consumption. In Spain, 14 hospitals were analyzed, studying the built surface area and the number of beds in the period 2010-2014. The results showed that in a hospital, the average annual CO 2 emissions divided by built surface area is around 0.10 Ton per m 2 , and the annual CO 2 emissions divided by number of beds is around 13 Ton per bed. These ratios will make it possible to benchmark hospital management and set targets for limiting emissions into the atmosphere.