For satisfying the network trend and intelligent demand of biopharmaceutical, we proposed the energy optimization consumption and management scheme of the drug green crowd data in the biological pharmaceutical cloud environment. First, the biopharmaceutical process are mapped to the cloud platform, which can not only adapt to the revolutionary changes in the way of biopharmaceutical research and but also build a network management platform for pharmaceutical research and development. Secondly, based on the green crowd, we reconstruct the organization structure of the cloud platform, production process, and value chain-driven portfolio, etc. Then, we divide the core of the cloud platform architecture into five substages. The green screening, reorganization, and crowd data processing will be completed by the cooperation of these stages. Finally, the drug green crowd architecture is embedded into the time domain conversion interface and the state transition interface. In addition, the state energy consumption model of the biological pharmaceutical cloud platform is constructed. The experimental results show that compared with the traditional task-driven energy consumption management mechanism, the proposed management mechanism can ensure higher throughput, higher effective flow rate, and higher effective energy consumption ratio.