The presented study examines how hospital buildings in Bulgaria consume energy, reduce emissions, and save energy. The study uses data from energy efficiency surveys of 38 hospital buildings, where 137 energy-saving measures were implemented between 2015 and 2021. These hospital buildings range in size from 465 m2 to 19,026 m2, with a total studied area of 151,306 m2, divided into three groups for analytical convenience. The study presents detailed findings on annual energy savings, with the highest savings achieved in Group 2 (G2), reaching an impressive 51.1% in 2021. Furthermore, the study analyzes the reduction in carbon emissions, with Group 2 again showing the largest decrease, reducing emissions by 2,097 tCO2 in 2019. These results underscore the significant positive impact of the implemented energy-saving measures, demonstrating substantial improvements in the energy efficiency of the studied hospital buildings. In addition, to highlight the financial and environmental benefits of the reduced energy consumption and lower carbon emissions, the study also offers a valuable model for similar initiatives in other regions. It emphasizes the critical importance of energy efficiency and how targeted measures can effectively contribute to sustainable development in the healthcare sector. This comprehensive analysis provides policymakers, healthcare administrators, and energy efficiency advocates with valuable insights and effective strategies for reducing energy use and emissions in hospital buildings. By showcasing the success of these measures, the study aims to inspire broader adoption of energy efficiency practices, ultimately contributing to global sustainability efforts.