Enhanced production of pharmaceutically important isoflavones from hairy root rhizoclones of Trifolium pratense L.

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“…The results were figured as a mean value ± standard deviation. The total phenolic and flavonoid content were in the range from 38.67 in Rc-15/9 to 59.96 mg GAE/g of DM in CD- 8 2017)investigated the influence of growth phases on phenolics and their biological activity in one red clover variety and found the highest value of total phenolics at a 30-cm plant height phase (41.96 mg GAE/g) and the lowest one at 50 cm of height (30.99 mg GAE/g). Compared to our results, these authors reported the significantly lower total flavonoids (3.87-7.32 mg QE/g).…”

“…The natural populations of the Trifolium genus are a rich source of secondary metabolites, which find an application in the traditional and clinical medicine as well as in pharmacy. Because of a strong biological activity of secondary metabolites, these components significantly improve the quality of both human and animal diet (Bustamante-Rangel et al, 2018; Kumar et al, 2018). The phenolic compounds are a large class of plants' secondary metabolites, demonstrating a diversity of chemical structures.…”