Enhancement of chicken lymphocyte activation and lymphokine release by avian influenza virus

Holt, Peter S.

doi:10.1016/0145-305x(90)90037-f

Cited by 7 publications

(3 citation statements)

References 24 publications

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“…On the other hand, mitogen-induced proliferation is a standard assay to measure the capacity of response to antigens [1,27]. Splenic leukocytes from L. ridibundus show a positive response to all the mitogens assayed; thus the gull antigen recognizing systems resemble those reported in chickens [10] and ducks [9].…”

Section: Discussionmentioning

confidence: 98%

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Muñoz

Fuente

2003

Pflugers Arch - Eur J Physiol

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The immune function of wild birds is practically unknown. We have studied several functions of splenic leukocytes from the gull Larus ridibundus. Considering that avian physiology is strikingly affected by the seasonal migratory cycle, those functions were analyzed throughout the seasonal cycle. The functions assayed were: adherence to substrate, chemotaxis and lymphoproliferative response to mitogens. Estrogens have been reported to modulate the immune response in mammals; therefore serum levels of 17beta-estradiol were measured in order to find a putative effect of this hormone on the immune response of female gulls. According to our results, gull splenic leukocytes showed a response similar to that reported in mammals and poultry. In regard to the effect of the seasonal migratory cycle, when the gulls arrived from the migratory flight they showed an immunosuppression as we have obtained in chemotaxis and proliferations assays. The immune response increased during the resting period and especially in the premigratory period. We have found a lack of a direct effect of the age of the animals or even the serum estrogen levels in the immune response of the migratory gulls. These results suggest the existence of other hormones and releasing factors, which would modulate the immune response in gulls, or a unique major effect due to the long flight effort.

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Section: Discussionmentioning

confidence: 98%

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Muñoz

Fuente

2003

Pflugers Arch - Eur J Physiol

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“…Antibodi terhadap protein neuraminidase (NA) memiliki beberapa efek perlindungan karena berperan untuk memperlambat penyebaran virus (Hunt, 2009). Vaksinasi AI pada ayam juga terbukti meningkatkan jumlah limfosit Th (Gioia et al, 2008), dan virus AI juga terbukti meningkatkan aktivasi limfosit ayam (Holt, 1990). Gambar 1.…”

Section: Hasil Dan Pembahasanunclassified

“…Gambar 1. Jumlah heterofil ayam broiler setelah pemberian berbagai dosis VCO dan vaksinasi AI Perlakuan vaksinasi AI pada penelitian ini, tidak mampu meningkatkan jumlah heterofil ayam broiler karena diperkirakan terkait dengan fungsi heterofil dalam sistem kekebalan tubuh secara menyeluruh, karena vaksinasi dengan menggunakan virus avian influenza yang sudah tidak aktif dapat mengaktivasi antigen ( Holt, 1990) sehingga akan memicu respon imun bawaan melalui ekspresi berbagai reseptor yang terlibat dalam pathogenesis (Kogut et al, 2003).…”

Section: Hasil Dan Pembahasanunclassified

Efek Amelioratif VCO terhadap Heterofil Ayam Broiler yang divaksinasi AI

Yuniwarti

2017

BAF

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Penelitian ini bertujuan untuk meningkatkan jumlah heterofil sebagai efek baik VCO terhadap pencegahan penyakit avian influenza (AI) pada ayam pedaging melalui peningkatan daya tahan tubuh. Penelitian ini menggunakan 40 ekor ayam broiler umur satu hari. Desain penelitian yang digunakan adalah Rancangan Acak Lengkap dengan kelompok pertama, kedua, ketiga, keempat, kelima merupakan kelompok ayam yang divaksin AI dengan penambahan VCO masing-masing 0, 6, 12, 15 dan 18 mL/kg pakan, kelompok enm, tujuh, delapan, sembilan dan sepuluh merupakan ayam yang tidak divaksin AI dan penambahan VCO masing-masing 0, 6, 12, 15 dan 18 mL/kg pakan. Ayam broiler dikelompokkan dalam 10 kelompok perlakuan dan dilakukan pengulangan dalam 4 unit percobaan. Pakan dan minum diberikan ad libitum selama 4 minggu. Hasil penelitian menunjukkan bahwa jumlah heterofil tidak dipengaruhi oleh vaksinasi AI maupun pemberian VCO, sehingga dapat disimpulkan jika peningkatan derajad kesehatan ayam setelah pemberian VCO dan vaksinasi AI tidak melalui peningkatan jumlah heterofil. Kata kunci: avian influenza, ayam pedaging, VCO, heterofil

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Regulatory T cell properties of thymic CD4+CD25+ cells in ducks

Shanmugasundaram

Selvaraj

2012

Veterinary Immunology and Immunopathology

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Enhancement of chicken lymphocyte activation and lymphokine release by avian influenza virus

Cited by 7 publications

References 24 publications

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Effect of migratory cycle and 17β-estradiol on splenic leukocyte functions in female black-headed gulls

Efek Amelioratif VCO terhadap Heterofil Ayam Broiler yang divaksinasi AI

Regulatory T cell properties of thymic CD4+CD25+ cells in ducks

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