Brassinosteroids (BRs) are the most important growth hormones which are steroidal in nature play crucially involved in growth and progressions of the plant. In recent years, advancements done in accessibility of biological possessions and approaches led to the most applicable mechanisms involved in BRs de novo synthesis, translocation and signaling pathways. The current researchers are also associated with the flexible roles of BRs. From the previous studies, it was manifest that BRs interaction with salicylic acid, abscisic acid, auxin, gibberellin, ethylene, cytokinin, and jasmonic acid in controlling numerous morphophysiological processes in plants. In this section, an effort is made to understand mysterious development and growth-linked either directly or not directly to BRs signaling and its intra-and interrelations with various phytohormones. This, in sequence, will support emerging extrapolative representations to moderate various valuable qualities in plants and address current encounters in agriculture.