Enhancement of OCT images with vinyl polysiloxane (VPS)

Abstract

Several studies have shown that optical coherence tomography (OCT) can be used to measure the remaining enamel thickness and detect the location of subsurface lesions hidden under the sound enamel. Moreover studies have shown that high refractive index liquids can be used to improve the visibility of subsurface lesions in OCT images. In this study, we demonstrate that vinyl polysiloxane (VPS) impression materials which are routinely used in dentistry can be used to enhance the detection of dentinal lesions on tooth occlusal surfaces. Lesion presence was confirmed with polarized light microscopy and microradiography.

A Long‐Term Clearing Cranial Window for Longitudinal Imaging of Cortical and Calvarial Ischemic Injury through the Intact Skull

“…Previous studies by Kang et al. reported that the application of transparent vinyl polysiloxane (VPS) to the teeth could significantly improve the OCT imaging depth and signal intensity, [ 28 , 29 ] which had good biocompatibility. [ 30 ] Thus, it has a great potential in maintaining skull transparency chronically.…”

“…In this work, we solidify the skull clearing maintenance reagent by combining the periodic and continuous irradiation, during which the temperature rise is less than 1 °C (Figure S9, Supporting Information), whereas continuous irradiation normally induces over 19 °C rise maximumly (Figure S10, Supporting Information). Previous studies by Kang et al reported that the application of transparent vinyl polysiloxane (VPS) to the teeth could significantly improve the OCT imaging depth and signal intensity, [28,29] which had good biocompatibility. [30] Thus, it has a great potential in maintaining skull transparency chronically.…”