An effect of solution treatment on microstructures and tensile properties of a new high strength Ti-2Al-9.2Mo-2Fe alloy has been investigated under the wide variety of solution conditions. The result shows that the solution treatment controls the stability of the matrix and the grain size. With increasing the solution temperature, the ductility increases but the strength decreases. The Ti-2Al-9.2Mo-2Fe alloy in ST condition has moderate strength levels (800-1,000 MPa) with an excellent ductility (20%~40%). The elastic modulus of the alloy in ST condition is ranging from 63 to 84 GPa, which is lower than other commercial beta alloys. Especially, solution above the transus temperature leads to equiaxed and coarsen grains, and results in well-balanced properties among strength and modulus and ductility. In addition, the properties can be also adjusted by subsequent aging treatment for a given requirement.