ENHANCEMENT OF WATER-EXTRACTION PROCESS OF <i>ICARIIN</i> FROM <i>EPIMEDII HERBA</i> BY MICROWAVE TECHNOLOGY

Huang, Ruihua; Han, Wei; Zhou, Yongchuan; Deng, Xiaozhao

doi:10.1142/9789812702623_0038

Cited by 3 publications

(4 citation statements)

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“… 30 Microwave pretreatment of raw materials significantly improved the efficiency of icariin extraction. 31 Icariin was reported to function as a regulator of adaptive immunity in 1995, 32 and subsequent studies have revealed antihepatotoxic 33 and antioxidant 34 activities as well as the ability to stimulate corticosterone production 35 and promote neurite outgrowth. 36 Icariin has pharmacologic effects on the immune, 37 skeletal 38 and reproductive 39 systems.…”

Section: Historymentioning

confidence: 99%

Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

Wang¹,

Ma²,

Zeng³

et al. 2021

DDDT

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Section: Historymentioning

confidence: 99%

Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

Wang¹,

Ma²,

Zeng³

et al. 2021

DDDT

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“…The microwave technique presents numerous benefits, including high efficiency, low energy consumption, short processing time, low cost, cleanliness, easy controllability, and low solvent requirement [104]. Both ultrasonic extraction and the microwave technique are often used to assist common extraction methods, such as water extraction and alcohol extraction, to improve the efficiency of extracting Epimedium flavonoids [75,102,105,106]. Furthermore, ultra-high-pressure extraction has also been utilized for extracting flavonoids from E. sagittatum.…”

Section: Other Extraction Methodsmentioning

confidence: 99%

Advancements in the Biotransformation and Biosynthesis of the Primary Active Flavonoids Derived from Epimedium

Zhang,

Tang,

Wen

et al. 2023

Molecules

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Epimedium is a classical Chinese herbal medicine, which has been used extensively to treat various diseases, such as sexual dysfunction, osteoporosis, cancer, rheumatoid arthritis, and brain diseases. Flavonoids, such as icariin, baohuoside I, icaritin, and epimedin C, are the main active ingredients with diverse pharmacological activities. Currently, most Epimedium flavonoids are extracted from Epimedium plants, but this method cannot meet the increasing market demand. Biotransformation strategies promised huge potential for increasing the contents of high-value Epimedium flavonoids, which would promote the full use of the Epimedium herb. Complete biosynthesis of major Epimedium flavonoids by microbial cell factories would enable industrial-scale production of Epimedium flavonoids. This review summarizes the structures, pharmacological activities, and biosynthesis pathways in the Epimedium plant, as well as the extraction methods of major Epimedium flavonoids, and advancements in the biotransformation and complete microbial synthesis of Epimedium flavonoids, which would provide valuable insights for future studies on Epimedium herb usage and the production of Epimedium flavonoids.

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“…The experiments and mechanics researches for microwave-assisted extraction were reported by many domestic and overseas literatures [1][2][3][4][5][6][7][8][9][10][11][12]. In order to make adequate use of microwave to enhance extraction efficiency, researchers try to find the kinetic law of the effective composition diffusion in the microwave-assisted extraction.…”

Section: Introductionmentioning

confidence: 99%

“…So far, the researches on the kinetic law of the effective composition diffusion mainly established some kinetic models such as the Garce-Ayuso L E et al [12]established MAE mathematics model by data regression and Li He et al [8] established kinetic models for Microwave-assisted Extraction of the resveratrol in giant knotweed on the basis of the Fick's diffusion law. Huang Ruihua et al [9] established the heat and mass co-transfer mathematics model for Microwave-assisted Extraction of the icariin in epimedii leave on basis of the Fick and Fourier's law. Yang Junhong et al [10] established kinetic models for microwave-assisted extraction of the rutin in hawthron on basis of the microwave-pretreatment reflux technology.…”

Section: Introductionmentioning

confidence: 99%

The Diffusion Kinetics Equation of Microwave-Assisted Extraction

Liu

Guo

2012

AMR

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In order to make adequate use of microwave to enhance extraction efficiency, the diffusion kinetics equation of microwave-assisted extraction was established on the basis of the theory of the liquid lattice model. By simplifying the diffusion kinetics equation, three simple relational expressions were obtained, which contained three experimental parameters (the extraction time, the liquid/material ratio and the particle radius, respectively). The fitting results showed that the theory curves were consentaneous to experiment results and all the related coefficient in fitting results were above 0.97 , which indicated that the kinetics model established is adaptive and appropriate in some range. Through further analyzing the fitting curves, it was indicated that the relation curves had different characteristics that one characteristic was the extraction rate obviously changed and the other was the extraction rate changed very slowly, which could provide a definite guidance for selecting the experimental parameters such as extraction duration, liquid/material ratio and particle radius in the extraction process.

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ENHANCEMENT OF WATER-EXTRACTION PROCESS OF ICARIIN FROM EPIMEDII HERBA BY MICROWAVE TECHNOLOGY

Cited by 3 publications

References 0 publications

Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

Icariin, an Up-and-Coming Bioactive Compound Against Neurological Diseases: Network Pharmacology-Based Study and Literature Review

Advancements in the Biotransformation and Biosynthesis of the Primary Active Flavonoids Derived from Epimedium

The Diffusion Kinetics Equation of Microwave-Assisted Extraction

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