Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin

Wang, Jiangru; Chen, Xiaolan; Wang, Xiaoyan; Kang, Qi; Shen, Dazhong; Chen, Lingxin

doi:10.1016/j.snb.2020.128581

Cited by 20 publications

(4 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Some typical application examples of MI-RFL sensors are listed in Table 3. 18,19,47,50,55,57,58,60,62,71,73,76,78,80–104 There is no doubt that MI-RFL sensors are on a rapidly evolving trajectory and enjoy significant advantages and diverse applications.…”

Section: Applications To Environmental and Food Analysismentioning

confidence: 99%

Molecular imprinting-based ratiometric fluorescence sensors for environmental and food analysis

Wen¹,

Sun²,

Zhang³

et al. 2023

Analyst

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Applications To Environmental and Food Analysismentioning

confidence: 99%

Molecular imprinting-based ratiometric fluorescence sensors for environmental and food analysis

Wen¹,

Sun²,

Zhang³

et al. 2023

Analyst

Self Cite

View full text Add to dashboard Cite

show abstract

“…The most common optical sensors include fluorescence sensors, surface plasmon resonance (SPR) sensors, surface-enhanced Raman scattering (SERS) sensors, etc. [50][51][52][53][54][55] Nowadays, the optical sensors have been developed to give dual-signal for multitarget detection, 56 connected to a smartphone for real-time and in vivo monitoring, 57,58 thus showing a huge application prospect. SPR is a label-free sensing method, which may report kinetic information on molecular interaction without using chemical labeling/tagging.…”

Section: Optical Biosensorsmentioning

confidence: 99%

State of the art in development of molecularly imprinted biosensors

Li-cheng

Miao

et al. 2021

VIEW

View full text Add to dashboard Cite

Biosensors are a class of smart devices fabricated for target analyte detection. A biosensor is commonly made of three basic components: a specific bioreceptor, a physicochemical transducer, and a signal processing device. The bioreceptor part features one of the more crucial technologies of a biosensor to perform specific detection of analytes. They commonly make use of various molecular recognition elements, such as enzymes, natural receptors, antibodies, nucleic acid aptamers, and even synthetic receptors. Then, the molecular recognition events of these bioreceptors can be translated into readable signals in various forms like electrochemical, optical, piezo/pyro electric, etc. Finally, these signals are mathematically processed for quantitative analysis. Nowadays, the great advances in biomimetic materials, in particular the synthetic receptors based on molecularly imprinted polymers (MIPs), promote tremendous development of biosensors. Integration of this field with artificial intelligence enables emerging design of advanced biosensors, which has moved from concept to implementation, meanwhile facing new opportunities and challenges. With no doubt, bioreceptor innovation based on molecular imprinting is an emerging driving force for biosensors development. In this review paper, we provide an overview of MIP‐based biosensors, and also their challenges and opportunities moving forward toward wearable devices are discussed.

show abstract

“…Some systems even use hybrid approaches. In these systems, it is possible to make sensing based on color change without the need for device reading with the use of nanomaterials with luminous, quenching, or magnetic properties 25,26 . Similarly, core‐shell or composite MIP structures prepared using magnetic nanoparticles equalize the precipitation steps 27 .…”

Section: Introductionmentioning

confidence: 99%

Recognition of human hemoglobin with macromolecularly imprinted polymeric nanoparticles using non‐covalent interactions

Aylaz

Andaç

Deni̇zli̇

et al. 2021

J of Molecular Recognition

View full text Add to dashboard Cite

Hemoglobin (Hb) is the most abundant protein in the blood. It is vital for the living as oxygen carriers. Some of the very pure Hb‐containing biological fluids are currently under clinical trial. However, the removal and purification of Hb from the blood are quite difficult, especially when it is at a low concentration level. In this study, the molecularly imprinted polymeric nanoparticles (MIPNs) were prepared using N‐methacryloyl‐histidine methyl ester (MAH) by mini‐emulsion polymerization technique for specific binding of human hemoglobin (HHb). MIPNs in monosize form have a size of 152 ± 4 nm. They also have a high binding capacity (32.33 mg/g) of HHb. MIPNs retain 84% of the re‐binding capacity for HHb after 10 cycles. The nanoparticles have 16 and 5 times higher binding capacity of HHb, respectively, in the presence of bovine serum albumin and lysozyme. Thanks to their high binding capacity and selectivity, MIPNs will allow them to be detected selectively for different target molecules. According to molecular docking, the main binding forces depend on hydrogen bonds and Van der Waals forces in the interaction within 5 Å around MAH molecule are observed through the amino acid residues of HHb at β1 and β2 subunit. The statistical mechanical analysis of docking showed that the free energy (ΔG) is −2732.14 kcal/mol, which indicates the interaction between MAH and HHb is energetically favorable at 298.15°K.

show abstract

Enhancing anti-interference ability of molecularly imprinted ratiometric fluorescence sensor via differential strategy demonstrated by the detection of bovine hemoglobin

Cited by 20 publications

References 62 publications

Molecular imprinting-based ratiometric fluorescence sensors for environmental and food analysis

Molecular imprinting-based ratiometric fluorescence sensors for environmental and food analysis

State of the art in development of molecularly imprinted biosensors

Recognition of human hemoglobin with macromolecularly imprinted polymeric nanoparticles using non‐covalent interactions

Contact Info

Product

Resources

About